Dominique Muller 1956-2015 Matinée des Fondations de la Faculté de médecine Prof. Henri Bounameaux Doyen de la Faculté de médecine, UNIGE 30 avril 2015-9h00-12h30
Au cœur de la cité, la Faculté de médecine de l UNIGE combine recherche de pointe et formation des médecins et des chercheurs. 1 880 personnes dont 1 200 professeurs et chercheurs 2 200 étudiants 66ème mondial (UNIGE) au Shanghai Ranking of World Universities
Des projets d excellence et une recherche d envergure internationale 2013
Les axes prioritaires de recherche Axes prioritaires de recherche Faculté de médecine Hôpitaux Universitaires de Genève Maladies chroniques, métaboliques Affections cardiovasculaires et vasculaires Transplantation et cellules-souches Affections hépato-pancréatiques et diabète Médecine génétique Affections complexes de l enfant et de l adolescent Neurosciences Neurosciences Imagerie et science de l information Relations hôte-pathogènes et immunité Médecine génétique Médecine de l appareil locomoteur et du sport Cancer Médecine humanitaire
Transfert la connaissance pour application médicale Comprendre les mécanismes Comprendre la nature Elaborer des modèles Elaborer des théories Recherche Fondamentale Recherche translationnelle Recherche clinique Diagnostiquer et traiter une maladie Oriente la recherche fondamentale
Financement de la recherche à la Faculté de médecine Budget de Fonctionnement: 96 mio CHF (dont salaires: 88 mio CHF) Budget d investissement: 1.5 mio CHF Autres sources de financements: FNRS: 25 mio CHF Sources Privés : 59 mio CHF
Une politique volontaire de développement des partenariats privés Création d un Advisory Board financier de la Faculté Responsable des partenariats Etude externe pour l adaptation de notre politique Projets de grande envergure (PGE) Cercle des partenaires privilégiés
Charte d engagement de la Faculté de médecine auprès de ses donateurs Lynn Durham Responsable des partenariats Faculté de médecine, UNIGE
Principes approuvés par le Collège des professeurs de la Faculté et le Rectorat de l UNIGE Vise à répondre aux besoins et exigences légitimes de nos partenaires privés Une volonté de développer une communauté de partenaires privés engagés auprès de la Faculté Lynn Durham Responsable des partenariats Faculté de médecine, UNIGE
Supporting High Impact Medical Research in Switzerland: Public Financing Tools Soutenir une recherche médicale ambitieuse en Suisse: les mécanismes de financement public Prof. Dominique Soldati-Favre Vice-Dean, Fundamental Medicine
R&D: sources of finance in Switzerland Total: CHF 16.3 billion
The SNSF funding policy Promotes scientific basic research Invests in young scientists Promotes international co-operation Promotes gender equality
Six evaluation criteria Scientific relevance and topicality Originality of the question under investigation Suitability of the methods to be used Previous scientific achievements of the applicant Scientific competence of the applicant relative to the project Feasibility of the project
Training and Funding SNSF/ EU Step 1: PhD/MD-PhD students Step 2: Post-doctoral fellows Step 3: Towards independency Step 4: Independent investigators Step 5: Networking & Consortia
Step 1: PhD/ MD-PhD students EMBO Courses & Workshops/ FEBS Lecture Courses EMBO Short-Term Fellowships Travel awards from Societies SNSF: Doc.Mobility MD-PhD, Marie Heim Vogtlin
Step 2: Post-doctoral training SNSF Mobility fellowships: Postdoc.Mobility EMBO Long-Term Fellowships Marie-Curie Intra-European Fellowships Human Frontier Science Program
Step 3: Towards independency Maître Assistant(e) 3/10 Marie Heim-Vögtlin Boursières d Excellence Ambizione
Step 3 : Independent investigator Assistant professor SNSF professorships Marie Curie Career Integration Grants ERC Starters and Consolidators Marie Heim-Vögtlin
Step 4: Established investigator SNSF project grants Division III SNSF Interdisciplinary projects Div IV Individual International funding
Step 5 : Networking & Consortia
International co-operation: Global Russia 2015? Global Research Council 2014 (Beijing) 2014 2014/16 2015 China Korea India Japan Brazil 2015 2013 South Africa Two programmes with the Confederation: Swiss Science & Technology bilateral cooperation programmes
SNSF Funding by scheme Bottom-up: ~90% Top-Down: ~10% Total: CHF 818.8 million
Partial association to Horizon 2020
An annual budget of EUR 1.7 billion A steady increase from 2017 to 2020 will bring it to EUR 2.2 billion
ERC-Funded Research Groups Faculy of Medicine Prof. Alan Carleton Fundamental Neurosciences Prof. Roberto Coppari Cell Physiology and Metabolism Prof. Emmanouil Dermitzakis Genetics and Developmental Medicine Prof. Anne-Lise Giraud Fundamental Neurosciences Prof. Daniel Huber Fundamental Neurosciences Prof. Stéphanie Hugues Pathology and Immunology Prof. Denis Martinvalet Cell Physiology and Metabolism Prof. Mirko Trajkovski Cell Physiology and Metabolism Dr Mathieu Brochet Microbiology and Molecular Medicine Prof. Stylianos Antonarakis Genetics and Developmental Medicine Prof. Christian Lüscher Fundamental Neurosciences
R&D: international comparison Gross domestic expenditure on R&D as a percentage of the GDP
Impact of scientific publications Relative citation index
Patents Number per million inhabitants
The Nature Index to track contributions by countries
Thank you!
Identifying and Supporting High-Level Researchers Qu est-ce qu un parcours d excellence pour les médecins-chercheurs? Prof. Jérôme Pugin Vice-doyen en charge de la médecine clinique Commission «Recherche et Relève» Chef du Centre de recherche clinique Journée des Fondations - 30 avril 2015
Academic track for MDs FMH PD Etudes MD-PhD Form. clinique Post-doc CDCscient Prof. FNRS Cloëtta Poste acad. 20 25 30 35 40 45 50 ans FMH PD Etudes Form. clinique Post-doc CDCscient Prof. FNRS Cloëtta Poste acad. 20 25 30 35 40 45 50 ans
Young talents are detected early Medical studies Bachelor: PREMs (program to perform research during summertime) Master: master thesis Options courses 6th year, possibility to perform research
Doctorates Soon after medical studies MD : Doctorate in Medicine MD-PhD: Doctorate in Medical Sciences (Faculty of Medicine) (3-4 yrs) PhD: 4-5yrs - Doctorate in Sciences (Faculty of Sciences) - Doctorate in Neurosciences (Lemanic School of Neurosciences)
MD-PhD, Doctorate in Medical Sciences Program of the Faculty of Medicine MD-PhD: fundamental or clinical research orientation Committee: President Prof. Francesco Negro Admission based on the quality of research projects and mentoring Possibility to get a competitive national grant (Bern) Mentoring (yearly) of doctorates by the MD-PhD committee
Outcome of MD-PHDs Career track - current employment (n=22, graduates who completed until 2002) Other Assistant doctors Research position in institutes/industry Senior physicians Assistant or full Professor degree Dr. K. Kuehnle, Swiss Academy of Medical Sciences
I would re-do a MD-PhD, if I had to do it again: 8% 3% oui, n=33 non, n=3 ne sait pas, n=1 89% MD, PhD performed between 1990-2010, Faculty of Medicine, Geneva 37 responses/43 surveys sent
Academic career for medical doctors (1) Clinical formation (FMH) Scientific intern *NEW* (2011) - 50% research for 2 years, funded by the Faculty of Medicine - 50% clinical - Goal: smooth landing after research, continue basic project, publish - Prolonged time to obtain an FMH
Academic career for medical doctors (2) Clinical fellow ( Chef de clinique scientifique ) Usually after 5-8 years after medical studies Awarded by the commission recherche et relève de la Faculté de Médecine Based on a scientific project (+ publications) Aspect relève 3 years, 50% or 80% of research Post-doctoral fellowship Anytime after medical studies Usually after a few years of clinical training Funding is frequently a problem!!! - Fonds de perfectionnement des HUG (commission HUG) - Fondations Sociétés médicales - FNRS (chercheur débutant/avancé) - Organisme d accueil
Funding of research Projects «recherche et développement HUG» ca. 50kCHF Projects «STARTER» Fondation privée des HUG/Louis Jeantet, ca. 200kCHF Projects «CONFIRM» Fondation privée des HUG, ca. 600kCHF All projects are evaluated by the scientific committee of the Centre de Recherche Clinique, and external experts
What is missing (funding)? Funding of postdoctoral fellowships (abroad) Chairs for young professors Project specific group funding
Thank you!
Clôture de la matinée Prof. Jean-François BALAVOINE Ancien vice-doyen de la Faculté de médecine, UNIGE & Président de l Advisory Board