Université de Poitiers Faculté de Médecine et Pharmacie. Thèse pour le diplôme d état de docteur en Pharmacie

Transcription

1 Université de Poitiers Faculté de Médecine et Pharmacie Année 2014 Thèse n Thèse pour le diplôme d état de docteur en Pharmacie! "!#$%#!%& ' ()*+ Quelles boissons prendre avec ses médicaments? Composition du jury ",!'-%#.&&%#/ "01 2!"34,!1##%0!.#5601 2! " 7#!%$01 2! " '%/#%&4(01 2 1",! " '%/#%&4(01.5"",!1##%0!.#5601 2

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3 8!2/ "- "' 9" "342 8 :"! 4( " 0 ; ( <2 8!2%1"9 ( " "" " ' "342 8 ( "' "34" = " (2! 2 #= " 0 = "5>.. " '2 ("" 2 (' " 2 ( " 2# = "= " 2!. 8? 0 " " ("9 ( "( " 2 1 " ' ; ( = 0 2 / " 0"("9 " 0 0'""2 ' 0 0 (2! "9 ( = " ( (0"9 ( = "9 0"9 ( " '9 ' " ' 2! 9 " (2

4 " $,=0 0''= A60B (" " C 2 $"'' 4" D 22 $ $9 "" $"'' <", * 2 $ <" * 2 $ < * 222 $'' ) 22 $ ' : $ $ $'' $ $ " A%&A"B0B $'' $ 0 ' C 222 $ C 222 $ D 222 "< $''" * 22C $ = ) 22C2 $ C2 $ C2 $''" = A%&ABA B0B C2 ''" "A%&ABA B0B E' ( D $ D2 $

5 22D2 $''" $3"' C 22+2 $ C C 22* $ D 22* $ 5 " * 2 $ " " * 22 $ * 22 $ " ) 22 $ $44C $ = $ $ " $ " $ $ ( C 222 (9 " C 2 ( " C 2 (9 4=" C 2 ( "" 4" D 222 ( D 2 (9 4=" ( " (3"' * 2 (3" * 2 (3"9 = (3" "2 (3" (3" '2 (3" = C =2 (3"= " C 222 ( ' = C 2! "< D

6 2 ( ' A& ( 0B C "2 < = C 222C ( C 2 " C 2 (9 4=" C 2 ( " C 222D ( C+ 2 (9 4=" C+ 2 ( " C D %&&F D %&&F D %&&F DC %&&F DD /= D) *

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

9 O $ $9 +CH" 2$ ' ( E9 "2' ' E< " ' < 0 ' = ' 2 O $ J= $9 CCH"0 "'" 0" "9 = " = 2.9 J= ' 2 ' 0 "("9 2. "9 (2 O $'.E3'09 " =" 9'' AB2# "9 :" 0 P %0 9 " 2 " <2. 9< "9 ' "0( 9 = '" " 94 2&( 3((0( < 9 ' ' ( 0' 2$" = =0 (( A!" Q0 B0 ' '" 4 = " 2!"# $9; "..%- + A. - B0 "'' = ( "'' J=" (A-=B " 2 "0 " ( : " ' A/%B2 9 "0 " " 09< < "(' (" ( = ' 0 2! E 9 "9 9"" 0 ( " " " 3 " '2 $ "E " 2 1' G= 0 9 ( = 0 E 5(*H0E' "(CH0E " (H H" "2

10 D * D 0 C+ C* C )0 D0 )+0* 0* 0 D0 )0* )0+ CD *+0C 0 0* CD0+ DD0) )C0 CC0CC +0D 0 C)0 0 )0D C0D *0 0+ C0D 3 /% "! %" %"!" $% $ "..%- 0..%- + &.% ))) - +0, O = " " " AR H E "0RHE "0RDHE B " = 2 O = E3" ' " L5 M AR 0 H " ( ( = EA$%0BB2 O " =' (" E 30 "9 0 E <0 " A!" Q0B0A60B2 0 = E L$ ( M 0 " -/ 40 "" " " 9 0 = =, = RD0CHS <' RD0H " R0+H2$ " =9< 3" ' 9 = " < 9 " ( " 3 " A$%0 B2 $ < " " 0 ( ( A50HB2& "<=',TU4 2 = 0 ( L " (M"9(0 =V 0"( " L "M2.( " "9"'( " "(L4 'MA/!0B2$9%&" "0 (

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

12 $ " ' " =, ( 3"'0 9 4" " <A8 0)B2 %0"))*"9 = " '."<% '"9%=" " - 0 < 9 ( " 2.L( =M " L5 M (" ="30"9 "9? 2 %9 0 (; ' " =2 <" "" 0" " 0 =' "( ; "S" "940 ("9 ( < = E 0 "( ; "2 %3"90 ( " " ""( ( 'L " M = 0 " 0 < 0 L=M = 2$ L=M " 0 < '( ' " = = 2! = 9 '" " " ' A' = 22C22B2$9 "( (3 " 0 9 "(' =V0 ( 3( ; ' " " "42 $9 " " <0 ( " "< = " R 0 H " " " " = ( 39 2 / 9 = " ( " " ;( A50CHB0A%&!A B0B0 " " ( "," " 2$ ""' I "4 "9 " " ( " 0 0 " 2 ' 93 "9= '" " 0" 9" " = =" " " 2 $9 "" 9 " ( " ' 93" ( "" " " 2 ' ( 1 0 = " 0 " 0 " - ' 9 = 2 D

13 ' ) $"" " '" 9 25 <",! " # " # $% 1 " ' = 0 "'' < "=,9 ""0 <" < 2 $9 "" A" " B " 2. (DH" ( *H" < " ' A "9' 9 0 B2 ' "9 ( ; " 9( ( ; ' 96 A= 0 <B0A@0B2. " = "2. = " ""( 5; 9=!" " 2. = " '" "9 9" " ( (" 2! " ' " 955" " ' ' " """9 A."9' 9 0B0A@0 B2 # " " 0 " " 9 4" < "= ' G " '94"= < A B2 "9 " "'" 2. 5<0 = 2 #$ % &'(!" 6[C\' " C[6[C5\' 4" 6]C5\' ".99%= = " A%B ="" '= "9 4 A" =" < 39 " 9 B0"9< 0 "94""""2 "=4 " 9 " 0 ' 93"9 "< 0 = " 9% '"9' = A%= = " 0B2 +

14 19 0! "' ' " < "("9 A - 0B2 1< 4"9 < ( ", < " " < "9; ' "9; " A<0 B2 "< 4 "9 < "< ", <" 0 < " " ' " ' G = 0 < ( "= " A1 0B, O ' C=I$0 "9 ' 2 O C5C=I$0 "9 ' 2 O C5=I$0 "9 4 2 O C=I$0 "9 2 "9 3"= E <0 "9 = E2$ < = E ( < "0<"L M "A-"0 B2 $ <"9 25*""", L& ' ()*%$. " " =4;" A@0B2 %3"9- "= "9 <"2!; <""9=" " ( 0 < ( ( = 2' " < ""'' (;(";" A.&0 B2 < " '9 25 """ (, & ' +$,!!," ' ' ' ()*$# " = " <0 " " ' ( 21 0 ' 93 "9 ' 9< " " '' "9 A" ( ("9% " "! "B0A@0B$ *

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

16 ' " <" ( " "< "A. 0 B2 $9 " "" '"" = 2 A" 5 B " = A( 0"0="PB 9= "( "(" "9 2$1/ ="= 9 "" 4" :"4'" ""4? =A/ ="=0+B2 ' *+. ="= = < 0 0 <'0 "0 < < " 0 " " 9'' = A' = 22C2 B = 2. ="0-4 ( ' ( D $I I )C0C $I I 4 " $I I 9% =2 1 "E "9 = " ; ( 0 " "= E "HH+ A!0B2." "" " CH " ( A-=B, /. -. / <' " < = )) )*% %)+,! "

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

19 " " 9 ( 0 3 2"9 " "9; = "9 2 $9 = " ' ""L5 M"" 2 '& %3"90 " L M" ' = L " ( " "X " ( M2 $ = ' G ( "9' ( "; " = " L M("9" "9 "(, L "(M0L "M0L "9JMA%&A"B0B2 $ ( ' = 4 0 =" " " A&0B2 19 9;". - " +0 ) H" ' 3" D H" " 3 2$ " 3" =V A."0 +B2 1 " " ; ( "9 " =" " A.&$0 *B0 A&0 B2 0 < " 2.E9 " CH" CHE9' 2 $ = & & "" " " " 3E9 "39 3E9' 09 " J= 0 '" "A= & & 0B0A B2 #^(" ^4 ^^="' =2 #$$$5 )+56787"!9" Groupe de population mg/j ' ' 5) 800 ' I "5* ' "A_* B '_CC 0_DC 1200!"#$# %&'% $ "= ( "9 0" =" <,

20 1 $9 A*+ HB0 "" ( ="0 <2 C =I$ ( 3 " A0* HB0 '" 9 = ( 9= " 9= = ' ( 9 " " 2$9 " " 2 0CH0CH" 0 =4 " "DCH"9 "= 0H"9 "= 5 CH"9 "= 4 2 : 0C H" 2 $ 3 A) H 0* H < A 0 0 = BB2 $ ' " = 2 6 " < E4 = ' "=" 9 2 $ " '"Q", 5 5 = 3 ACC HB2 ( 9=0 =4 ' "'2 1 " 9 " 2 $ ( " 9 " " 2 42 ; $ " <0= ( "C$" " ( " " K5"2 #$< 2 ; 1 0!"6$8"!"3 7 = 4 > < )=^ H%&. = C= *=! 3 10%0 /0/0/0/D0/)2 $ " ( '' = 2 ( " ""9E ' J= "9E' "2 $%&. 955" '' ""'' ' " <"= ( 9J=2% '" ( %8 3 " 2.( 9 " " "9J=2

21 (" 0 " = " =0 3? " = < 5 A$ " A B0B2.9<" " " "9" E J= 2# " AC $B C H" " A-40CB2 $ < 0 9 "9 9= 05' "9(" "9 " 2 '' ++ $ 0 ' 4 0 2''0 (A ' ' 0 4 B" " ' "< 2.9" " ; 2 % $ "< " 9 2 $ - =I I 0 G = " " 0 4 # (0U=" A!"9 ="9 = "';0B2$ ' 3 9 A' (B" 0 (" " ( ; ( 2.5 ( 9< 9 = " " ' : " AR0+H"(A (B BA$%0B2. = 9< 9 = "9 " 0 ( " " 0 " " ""( ""("' G A$%0B2 ) $ ' G C0 U=I I " ' 0 G - + = " " " ' 2H"' G " ' 3 ' 2 $9" U ' " " ' - 9< ' ' "' G 0H 0"( 9% = ()H4 5# (*H2 $ " ' 9 "9 = 39 C0 " 9 = "" ' 2 '? "4 " ' 0 " 9 (( 2 $ 5 ' W ( "9 ' =0 21 " " 0 9 " ' " A*0HB" ' A B ' " ( A=!3 0 B2 C

22 " ( H " " " " < " AD<I3^*=I3B0+H(39 < A 5"" D<BA%&AB0B2 % 0 ="*2$ - " 4 " (D0U= ' G (U= A0B2 $ 3 ' =V " 3 =V ' 2! 9 " ' "("' " A6 0B2 % $ ("'" - A " = B0 ( "'' 0 "'' A0(0 PB A! "0 B2. 0 " C "'' A%! " " ("" = $ ="50 B0, O $4 (' (Q"0 " 2 O $ ( 3 ' < A0C C0CHB " 405" 4< A00H """ B 0+5" 4< A0C0H """ B2 O $ " ( ")" 2 O 1(, "0(.0( /2 O 1 < ("'0" "9 2 O 14" " O 1 O 1 Q" $ " ( ( " ' " " " 9 (A`0)B2 ) $ ' "9 A()DHB( /0 = ' 2." " 9 ( =" A- (0DB2$ ' ( "*= " ' AC$B2"''( "9< 0 K2 D

23 #<#)5 4=;?!!"3 / ' =I$. ' ' +5. ' ' C+. ' C5D. ' C5C. ' < 5* /4 5. ' " ' *5* ( 5*., *, / 5. D5* "// % ( " 4 #.$ "9% 2. " ' " = 2. = '(" 0 ' " 2.'( (, O )CH"" O *H"9 " O *H"" O CDH" Q" O DH" O H" O H" O 1 ' " 4 A! 0)B2 ( $ ' 4' " ' "< 2 $ ' ( ( "C 5 =J ( 9 " 2 "5( "9( ( E( 5 A39B 'A C B0 ' AC5 B0 " = A39)DB2 $ ' ' " A! 0B2 $ < ' " ' "" < "0C=IU=I32'0=I3 =I3A%! " " ("" =$ ="50B2 40 " 0 ( " "='2 "5( "+)E "0"CE +

24 ' ( 39E( 5 2 ( ' ' ( " ("9 =0 ("" A0C 0C $I`=B = '< < AC5D HB "0 ( : '" =" 4" 9= " AK" 0B2 "" 0"' 2%9 " 9 9 ' E " < " E <A! 0)B2 2 ''" < % $ = 0 9 " ( 0 = "" " ""2.E " (0 " ' 0 < E ( <2 = " 0 ( = ''0 " '' 2 = ( " 94 E " " " : = " " < A10 B0 A.0B2 9"9'' ' < <E "0( ; <2 %% 4 ' 2 $ ' 4 ( " %0%"9 " : = " (= 0"9 (0 "9 < 0 = " 4 " 2 0 "< 3? : "" 0 4 = "9%! 2. ( : " < '' " " =4= 4 = " "=(0"9'' "=09 ' ( '"9 2$ ' " ''" 0 " "9 " A.'0B2$ 4 ; " "9 " (A.0B2 "9 '' ' 2 = " "" " A' = B2 (" "' " " " '' " "" "" = " ' = 2$ ' " ( ( 3?"9 = *

25 " 9 " 9'' " 'A0B2.9 (" " <.$%%1$ ' a " " ' 2$ ' 9'' " '" AK" 0B2 2 ''" <' (Q" $' (Q"" " ' ( 0 '( 5<4" " ( " <4" " " " 5' 2%( ' ( '0 ("9 ' ( 9 = " " 2. 4 "0 " ("" "42 1 " ( =" ( <"= (" A`0)B2$ (" " (" A`0)B2.4 0" 0 " ' 05 " "( = 2 ', $9 L = M ' " ' = 2. ' " " ( 4 9 A%& A B0 B2."( ;'" (L = M0" = = "L"UM0" " "9 ( (0 ' 93"9 " = 'A%; "3)++X "" "3)+C "" " =BA$=- 0*B2.9" * 9 1! E" ( ` = 1 =0 Q " 2 " " X "" = "< ''" " < ( 2.0" " ' 2( (9" " ` =1 =""X%0 (= E,$"a 2.' ' % )*+0 ))+ < 5# - *A$ 0B2((" <0 0 " = 0 " U " 2 )

26 ) $ " = "H- )2 3 " = ' G 2 0+H" ' G 0J= "" "CH C 21 0DH"2H" " " = ' H " " "2 $<" " " " H" 0 ' " <''A:"0 222B0" (H "9 ( 40" (DH" ("9 A%&AB0B2 ) %" " 0 : ( ("( " " 2. " " KA " "7 0B2 #<$ $ &!!" Molécule Teneur en mg pour 250 à 500mL Caféine Guarana Taurine Ginseng Glucuronolactone Vitamine B Selon la vitamine Sucre $ ' ( " )DH"" = " ' G A H 9 '" B0CH" H"= 0D+H"( "" == 9'' 2 ) *!"#$# % %&'% 1 = " < " '' = 09 " " = 2 ). ( " = 0''" " = " "< ( (2H"' " " " ' 0''" "9 " " <A' 222B2

27 .9 " = " ' A +0C H" "" = B'" " 4" A' 222B2.9 " 0" " 4 2& " '' " 0 <= 9" 2$ ( "" 2 ( " = 5 0 < )(0 ( C2$ ( /D 42 ( ( " ( 0" "4 "2 "C' ( AC C "" + U=B < A " " ("" =$ ="AB0B2 " " = " ' " " "=" "0" = " 9 " " 2 $ - "" ' " ( C 3 * "" ( '' ' A " B2." " =0 955" = "9 " A 9 B" 9= 0"' G '2." " = " ')+ ' & Q$ E ( " 0 ", O. "( " '=2 O %= " " ' "( =2 O %('' " 9 == ( A "9= "9'4=B2 < " " ',="A*"'' B2 $ ' ( " " 9 =; A HB2 $ " 0 ( "9=;9 ' '2. " 0 955" 4" 0 9"" 0" "'' 2 %""<"9 2 $= " ( "9 "=(" " = 2" " = " ' "=4=2 9 "9 ( " 32

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

30 (0 (+C0H0( 'AC+0HB AC0*HB A( ' G ""="< 0B2." 0 "9 - " =2 : "9 ( 0 3"9" " " 2% (( " " =" " ''A '(0B2 + #""9 "( " ""9 3' ( " " 3A-=B2%5"" " 0"" " "( ( A '(0 B0A6 "0B2 $9 4 (0 =b : " "' " 0" 0 9" 0 "5;0"90"" '<2 # A" ( 3 'B " = (9=,'( " = 0 ( ( 0 ( "'2 $ "" = : "" " 0" 0" ( < A%"0 B0 AA B0 B0 A6 "0 B2 1 "4?" "0" ( " 0( 2 $9 "' = " " A ' (0 B2$9 4 9 ' = 09 2( " ' ( " " A%0B2 98&;';'; &);!9"

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

32 C 3"' A 3"' B - A- 0)B21 $%8"9%8 " 2 19 " 9 ( " '" "'' "' A 0 3"'0 < 0 < 'B0 = "' 3"' A HB 0 " 9 == A/ 0 B2 0 = " "0 3"'" C " 3A= 0B2 #<$$ ) ))+ && 5A"BB8>$7$!!/" =) C!!" A 1 A1 A A A 8D" +0* *0C 0+ D+0C * 8." **0D *D0 *+0* *0* **0) = " C+ 0D " 0) 0 0 0C _0 7"&; 0A^0+B 0DA^0B 0CA^0*B C0^AC0CB *0CA^0B!"!!" < " D0* )0C 0 D.5A; ) 0* +0C!! <,EF" D *0 0C.5A; D *0 +!! = " + C C ).5A; C 0C D!! 4" )0+ 0* 0 D0D 0.5A; C C!! " +0* 0 0C 0 +.5A; 0 0 0*!! " 0C '0 $93'" = "" 0 " " " " 0 "9 9? " " ( <"" 2 $ " ""=( = 2 (; ""'' ' GA 4 "0CB, O ', 9 ( "="( A(" " B" 5C '2.""9"9 ' 9 " (,'0'0 ' 2 D

33 O $ ", "( "9 = 0 " '' 2.9 " = A 0 E0 B " 4 2 O $, "( "9 = 0 2. "9 ( 9< " 2. "9" ==2 O $ "=, "= "( 9 = ' "9 " ( C 2. ( " 2. $ " = 0 ("9(" 0D 00A-=B = E - A4" " " '0B2-7;; % )!!0@!!4 1 1 )G! "3 1 0 ( =" < 0""( 0 (" 3 ( 0 2." (" (9 " " ( "= " 2 $ " ' ( " " " "9 '' 2 < '' A( 0 '0 0 0((B0 A(= =0 "9"B0 A =0422B' "=A PBA 4 "0 CB0A0))B0A/ "0B2' " < "'' '" 2 1 )0 = 9 9 '' ="9 = " " " = 2 (" " '' 0"' ( <A- '0 B2$" 00" 9 4 "9''" +

34 ' = 2''0 " ( = 9 " " (2 $ ( " " A4 B ( " " " L " M L =M ( (" " 2!; <" "9 3 " 0 " 0 "0 Q"0P2 " ( = ( : " ( " 0 " "4 A.=" ""7 "" "7 2B2 1 % (" "'' =" 0 ( 94 (5 " 2 " = " "9 '' ' 0 "9 " "9= "9 " 0 ' 0(; 2 - = " " 9 ( " 2. " 2! = ") V ( " 0 C ; '' " ( CH"'' ( 2"" " "" " 9' " 3 " 0 ' " 9 " 4 " A% "0B " ( (' E962 < " " 0 " '" "9 " 2/ : " ("9 " "9 " ="9 " 2$"9 " " = ( ',9 0 "0 9 A!0 B2 ) $9 ( ' "< 2 "9 " ( " " """ ' "9 " '0955" =""9 " = A!0B2 (' 2= " K " " "("2 *

35 . 9 ( " 09" ' " "" " " = ( 5 A% *B2 #<$$$= )+ ' ' 4!! " & &;. "9 " A` B 6"=' 64"I K" (" == =" % -= "9 " = $ ' " ", ' 5 " < =0 ( < A.! <B <A! <B < A-=CB2 08; &' '3 (H E!!I"3 $ '( ; 0 < 0(= 2$ "''( " ""', O $ 2 O $ ' ( 2 O $ '< < 2 O $" " = 2 " "(""AK"B " " " A"B ( A.BA!0B, )

36 & $ ' " " 0(; ' '2. ' ' " " < = ( " '0( E4" 2 "9; ' 4" '"9; 9 A <BA/" 0B2 $ ' "<, O " ( <4" " 0 "&%160"9.ZCA' = 222B2 4 ( " " A' B ( ( ' 2 # "94"4 ( = 0 ( ( ' " 42.5 ' ( "'""'' 2-0" ( ' "" =,5605&6 05.6A-=DB2 O " ( 3= 2.9 ' = 5605&6 05.6" "0"9 9 " 15=" =3= "9' " ' 3= A!0B2. 4"0 " ' 9= 2 J2% ' (;!9"3 /0/)'.9 (( " '".ZC2$ 4' " ' "5<4= ( "'0 "0"9"0(" "9<4" 2 " "9 "'' 2 <""'' '0(" ' 0" ' " = " A-=+B2$4

37 " " " " E9,.Z%0.Z1D0.Z.)0.Z%0.Z.)A/" 0B2.Z % C - % % I) %) = 4!9".4(;"'' 4, O 4 = " " = " 42 " 4 = " 9 " ' "9 H 9 : "' 2 O $ 4"9 ( 0" 9<" = 9 "' 9 ( "4" = 2 O $4" = " ' "9 I 4 = " =" " = " 40 = (/" 0B2.4( (" "(" " " 9= 2$ ( ;"( "<4", O ( " 0 ( "9 " '' " " " 9 "9"=A " ' " 'B0'' "52 O $ " ( " ( : " " '' 0 ( '' 2 "=0 ( : ( "9'' " 2 74" 0" " "9 " = " " " A! 0B2 */1 $ =4 5 A5=B "9''< 3 < " " 2 ' " ' " % /"=. 0" =!15C2 1 = 0 ( "" < 0 ""90" " 0"" 5 0"44" 5 2. =4 : "" 9 " < ' ( 2

38 $9< ' " 5= ' " = " ( "("0 4= "=!152.( 9 "" " 2 4 ' <" 5=0 ( ( 2 ".Z%;<" 5=2. 9< ' =".Z%; =!15A/" 0B2 ' ) $9 ' " 3 " 0 ( 0("<2 1 % &. ' ( 4 2#'" " ( " W ; A-=*B2 /?% &:'>!!/" 1 $9 : 3 9 " ' = " 0 " " " " = " 2, O $ ' = ' ' " ' 2 O $ ' 0' ( "< 2

39 O $ ' ' =" 2.9 " "?" 9< "9 " 2.' " 0 " "'' " 2 $9 " " 9< "5("9 A I B 2 I " "5 A-=CB2%"0<"5(0 " " A)HB "9= 2$ (" " =09" < $I2 $ " " = ( " 9 " " A 0 PB A!0 B2 #' 3" " " 9= 0 ' " " W ( ( < "' "( " " " 9= 2%( "9(( " 0= "'' 4"9 (;" 2 # " "' =' (0 ( ""0 " '' " "9 " 2 < "< 4 "9, "4 A$ 0B2 / # "4 ( " 9 " " 9= 2. " " 0 ' "9 =2 ' ( "9 =0 "9 """ "< " 4 ''2 $ "9 = "< 0 ; '' " " " A$ 0 B0 A! 0 B0 A! 0*B2 # ("9 "9= " 0 "' " " " 2 '' " " " A9 0 "0 9 B2 " " : " '" ( " = =" " A$ 0B0A$(;0B0A! 0*B2

40 <"'' 4"9 " F2 #$K)) % & 4 %! " 4) % & &% & $ 1 K "6= %"L'' M.< K" == $ 0"; " "0' ( 9 " " "' ""' "=(2 $L'M9 " " 2. ( (' ( "< A B < "=" 2<, " " ( 42!"' " ("9 " " 2!"' "9 " " 2 $ <" '' $9 ( 9< " '< " " " 2$ " ' '' '< : = " ' (" " ' '' 2 $ ",<4" A.ZCB ",3= $ " " 3?" " 9 " " " 4"I3= < 2 '" " "9""E4 " 3= 2

41 $ 1 - = " " '< " " " 2$" ' '' '< : = " ' (" " ' '' 2 ( 6"2# " "9 " " ( = " 2 $9(( "' 2 4 ( " '2 % % ( " " = "'' 4 "9 0 " (< " 2 2 1' G = 0 ( 9 " " "" " " " ("9 <" L < MA' = 222B2$ <'" ( " ; " ( A' $ B2 % < ' 0 0 = ( = ( " (, 0 (4<0 40 4Q0 (" 04 ' A.=" ""7 "" "7 0B2.E " ( = ( 9 4=" (2$ ' " = " ( "' "( ((55 (" 2 C

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

43 (,))H" 0 ="H" A< B A1 0 B2 " = 0 ' ACHB' A+HB ' (2 ( " "='0 = 9 0 = 0 " 2 $9 " ' ""< ' G, O ' 2.'<( " ""'<""2 O ' ( "'' ( '<" 9 0" " " =2 ' " " 3 >=0 0" 0A1 0B2 $ " "0 " = 2. ;"( ( "" = 9= 2 " " " 3 "9 "2 $ " 0"= " " " 0' ( 9 " = 2%" ' "'<= "( (A" AB0B2 : 1 ; % $ "( 0 " ' ( ' " ( 0" 9 """ 2.9 " " 21 " "'' " """ '< ^'<a0 " ' " 0 ""'',"' '<0" " 0 "94"<4""9 2$ ' "< ( E0 ' 0 : " " 9 " " A3U(0B2 $ " ( ( ( 40 (4<0 Q0 (" 04 0' =0 9 0 A A B0 B0 A 0 B0 A 0 B2 %' "9 ( 0 ' "9 " " ""< ( " "9 " A 0B2 5 1 ; &. < " ( "0 " < " 2. " 4 < ' " 2%9<" "<44'" A' = 222 B0 " ( ( ' ( 2. "V ",9="""0 0 ' ( AK" 0B2 +

44 0 F" " " ( " 2 #K4 ; 3 % & 64Q" %(( % U " % = % < / 4 $(4<^$(4<a Q^1 a $(" ^a ^. a!4 ' ^.a =^( "a ^ 4a %" "^- <a0- ( a " ^%a %" "^/(( a %""^U"a %"E "^Y a0% a %" "^% " a0 a %""^$4a0. a %" "^1"a 23 % " ( 3" ( " 0 < "" " 3"' ( " " A%&!AB0 B2! " 94 " 9 " 3 "9 =0 " 3 " =0 " 3 " = "0"3"" " " A6 " 0B0AT 0 B0 AT0 B0 A- 0 *B0 A$0 )B2. 4("' " 3" = 9 "0 (; ( " 3A- 0*B0AAB0B2 $ =" ' " 0 <, O $ " 9"?2 O $ ' (Q", =0 = 0 0 "0 = 0 0 P O $ ', =0 = 0 " ( " = 4<4 0 D90+95"4"= A16/B09 <4""= O ' 2 O 1 " 4"A/" 0B2 L=95- $3" " " " (.Z%0 = < 9 " " 0 "' " "5( " 2 $9 " " =.Z%" 40.Z% "9''< =4 5A-=)B2$4 =" " " 4 5= 3 " *

45 2 1 3 " ( = 9 " " 0 ".Z%A! 0B2 / ' (Q" " " 3" 0 <A ' =B ' " 9'' ".Z% A6 40 B2. =' (" ""9 " ', ' <4" = 5U (.ZC :9E4 2 ' 0 = 0 D0+5 "4"= = 0 " 9 (.Z%A!0B0A/ ( 3@ ( 0+B2$ ( ( " "" 0 9 U =2 1 0 ' 9.Z% " < '2 $ =.Z%0.Z/0.Z%D0.Z/D0.Z.)0.Z.)0.Z1D0.Z.Z%C2 7 "4"= " 9".Z%0.Z/0.Z.)0.Z.).Z1D2 E$% L=95-4!!-"3." 0309".Z%( " 27 " " 9".Z.)0 " " T ' A = B" A6 40B0A1 "0)B2 51 "9 20 " 0 " " 9 ".Z% " E ^ 64(a AE" E B 3 " 2$ 9 9E4 5 " ( " 3 A/" B0 A@ 0B2$ "9"3" ( ( 4" A0 0"9=' 0 = B0 9 )

46 2 9 ((" 30 "( ^$( a "<A=0)))B2. 9%&!" "9*03" ".Z% 9; 9 " " = ''" A%&!A"B0*B2 %5""9".Z% 0 9 ($' 3"3" 0.Z% A!" $0 B2 >5#= *0 " " = " =" "9 = %A%%BA- 0*B2$ % ' " 0( " 2 " " " 0" "< " 2( %%%/ 3 ( "9=;2 '<' "03" %%0" / 40 9 " 3" 0 0 : "' " " ' <' ""A640B2 %/0 " = " 955' 2. " 3 " " "3" " "!, =0 = 0 0= "4"= " "" 6`)2 $ (, ( C H" 3" ( ""* H" 9 " 955 ' D H " " = "2 %( = 0 ( ""9 CH"9 "955' "= "2! ( "4"= = 0 ( "" "< "DCH "4"= CH = 21 " " "< = 9 9 A6 40 B2/"" "0 ' (Q" " 9 " %2! 3"9 < " "0 9 ( ' <' "' A! 0B2 =?" $ 5=( ( "9=;.Z% ( "" " 4 < ( %%21 "" 3" 9 = " " " 6`5 9 ( 3 " 0 9 ( " 5= " " C H2 ' (Q"", U ' = 9 ( CCc!" = Cc!" U ' ( (;""9 ( " 5=A0B2 "3" 5= : = " " " A/" 0B2

47 03" 4 "9" "3 9".Z%0 " " " "4 (;"' 3" 0( " 3"'3 ( " " " 2 $ " 3" " F2 #K$ & ; % & 4 8)) ) ( ^Ya %( ^ a $( ^$( a ( ^a K ^ -"^-"a &' "^%" a &"^/ 4a " e"" ' A/" 0 B A8 d "0 +B A%&!AB0 B A1E0 B.^& a ^= 'a ^ a "^K "a &< 6 < % " %07 ""!4< /E" E!" E ^/ a E ^6 a % E ^F <a! " 44^4 a. 44^Y a % = T ' ^. "a %< ^a ( < ^F a. ^"a "" = %= '' ", 4 % %" E^ a E ^/"a & <" ;0(= %((. E ^ = a 0 (=0 < & /^/ a ^Y'a.E ^$<a 7 ^Fa " " (^.<( a $ 0 "K6 4 % <.E^F Ua "".4 "^"< a!4< 1 ^4a 1 0 ^ ( a < P (^. a A1 "0 )B AY 40 B0 A8 d "0 +B A8 d "0 +B A/ 40 B

48 %" %( < %5' % 4 %4 ^@(a ^4(a &^ = a E ^Ka '^&< ( a ^a K " ^. a K '^Y 'a. E <^8( a 1 <^ <a ^. a ="^&(a < =^=4E a! (^.a (^a (^( a /""^&(a.^ <a!4"^ "a 7"^64""a 1" ^! a %"^%a $ ^.E a '^4a = ^@4=a 64=4 64 0" '' 6K 64=4 4"".= (0 64 %5. E^ a >"P 1 " C %5 == = 6 ^ a " '^K = a " '^. ak " '^ $( a."=^ (<a =^/ a "^( a 4 " ^ a 0' 6 = " 0 % < 1"^!a "" %= 1 ' ^ <a -"^( Ea ' ^( a "^"4<a ^8a 0 12@2/ 1082! 0 2%"2.!%8! C0*C, )5D

49 " /^ "a & 0 ( % $" Q^F4 a ( % = - 4^1=a "0 %' ^ 'a 0 <4"^<4a0 0 <4a P % 5 %'E^F a "0 3 " " " '" ' A U'? " " ( ">" = ' " 2B %( '".- /E^K "a = " & 0 4 =0 0 <0 "4=P 1 < ^=4a K=04 ( "^ a =0 "4 " = ( '^` 4"a A.=" "" 7 "" "7 0 B A%&!A'B0 B0 A1E0 B % " ("''"3" 0' " =." ' " "' =2 " ( 3"9 = " 9 " = " 2 1 " " ( 3"9 = ( (?" 9".Z% %2 T "3"9 =" 9".Z% ".Z%2 $9 " 9 " " $" 3"9 ="<' 3 " 3 " 9"" 0D =" ( " 3"' " "32' " " 2 $ " " < " "H0 9"" ' " H " 2 $ 3"9 = " " ""9 ".Z% =4 5AT 0B2

50 # " " ( = "9 0 ( ^a (*$"3"9 =)C0 ( = " C H" ' " ( ( "9 " "; " ("9 AT0B2 (0 3"9 =" "'<' "^ ' a0"9 ^ a0" ^.a0" '< ^.'<a0" '0"('< ^ ( a2. "9 943 "9 = % " " " AT0B2 $ ""'' "( 3=' ' 9 "3"9 =" 0; '' 2 $ 3"9 "" 2. E4 < " =" ' :"9 26" U 20*0 9'" E40 "0 9 ( ".Z.) ( " 2 $ " 9 " 3"9 ACc$B 9 ( ".Z.) 2& 0 ""0 ".Z.)0 9 ; A6" U 0*B2. 3"'"" " " ( " 2. 3"9 =0 9 ;" 5 " 9".ZC2." " (3"9 =3" ( ( '0 ( %/0 " 9 U ^ Ea 4 " %/2( " C3"A$B"3 "9 ="3""9 2% 3( ' "" C ="9 U2 0 ' 9 " " 9 ( " ( " " " 2 $ "<3"'0""" " " 0 " " ' " =" 9 " " 2. 0 ( = " ( " 9 U0 5 9 ( " 2%"3"9 =3" %/ ( A 0B2

51 $ 3" = 3"9 ; 4 < " ' 2 ( 3 " 2.90$ 20 " ( 3 " = 'G " 5 2$9 " "*' " " "" C= ( 3" ="9 <" ' 2 $ 9 ""9 03"'9 ( "9'' =' ' "< " A$0 )B2." " " 20D( """ E ^64(aAC =B.Z% (("$"3" =2$ = "H" ' " " "' " "5("9 AT0B2 $9'"3" = d ' ^. "a0(.z.)0 " = " 9& A E" 955" 9" " = =B " " AT0B2 $3" = " ( '.Z%.Z.)2 0 "9 (3"' ( " 2 3 " = "0 9 = < " 4 4 '' <4" 2 " 9".Z% ".Z.) 2. " " " "44 "( "3"= " "9 = " 9& ( d ' 2! " < 9 21"9 9 "9''"" E (3"' " ( A=B ($"3"= "' 3" 30 ( Ad0B2.3" =03"= "" " " " 9".Z%.Z.)0 "( "9 (3"' ( 2 1 = 3"'0(" " 9;0 ' " "9 (" "3"'9" 2 2&&&*.9 ((" A' 2222CB0 ' 0 = " ' " 9 " 2.9" C

52 " " 0 ( 0 "90 =2 %'"<" = " 0' " 2 $ ' 0 4' " ' "< 2$ ' ( "='0C( ( " ( W 3? "9 = " " 9 " A B2$ " ' (.Z% " 4 " "" " 4< A-= B2! )5!!E"." 4 " 3, O < : "=4 "9 "= " = : = " 42 O $ ( " ( " 4 0 = " " 9 = " '< "9<4= " "9 ( 2 O $ 4 :" A! 0B2. "( "(", O $ = : " " " ' 5" " 2. " ( 39 C H " 9 ( ".Z%2 O = 0 ( E ' = " " ' ( 4" 44 " ' 0 = " 4 A0B2 O $9'" 9J= A FB0 E ( 5 E J= ( "" A (B : = " " " ( " 9= " ' " 4A@0CB2 D

53 0 " = ( "'( "5(" ' =( 39)D A! 0B2 #K$$)'M' ) %%8EE/" ) #%% # C CHC%" # C &( 5 C 5*2C C5 ' 5 +52C 5 %"" 5* *D5 5* C %"" D5 )5C = C $ ( " ' ( ' ""'' ' G29 5;( 9 " " 09 " ( " ' 27 ""9 0 " 2 $ ;1 %& $9 4=" ( " " " " ' 2 " "9 ("9 " ' " 4 ' 0 ' 0 ' 0 "0 ' A 0 "0 =B (" ="' ( "( = A%&A B0B2 $ ' " 0 ' " "> = "9> =2% "( " < 4 " '< = > ="9 ( A " AB0 B2 $ ; 1 9 ".Z% " " < 0 " " ".Z%( "' A" 0 ))*B2 $ "'' (, O $9E4 ".Z% ".5 " ".Z% " " ' 2. ( : = " ' " 9= "" ''",< <"9 '< ^.'<a2)*) "9 ' ( 2$ 3G030=" ' (*$"

54 '( < ' " =2 "< 3 3 = " " +C = " '< 2$ "" ("( =" ' 2 ' 0 < '< ( " ""2$ 9 "'< 0 "5 (" ' " "C0*02 " "D C*0$I2. < 09 9; <" " ' ( = " "9" " D0 0 2 % '< = " ' " " 9= " ( "9 "''" " A6 40)*)B2 O $9 E4 ".Z% ' "9 ( " 1 " ' ".Z%0 9 " 0" "0 " ' ' " " A! 0B2.9 < "9 0 E ^ $<a2 '' 6f== 20 "< ="( " "" E " 0C =2# =9= E 9 = """=" ' " E 2$ <"E 0" 0" ' " < 2 $ = " ) H" E ""H" " E = ( ' 2$ ' ( E 4% : "" " " " = " <" = ( = " '' " A '' 6f==0 B2 O $9"E4 $ " " 0( = " ' 0 : "" ''2.9 9<" 9 ' "a ^ ' 2 D0/ U 20 "" (=( 2# = G "" C 30 D =" ' 2% <30""="E "^Y '<a0 < 0 " ( 2. ".Z%2$' " " 0 " E "" 2$ ; " (" ' 0 " E "2 $ "" E " " " ( ' 2$; (" =" ' " < 0" (9 2#"" ' < "9""H ( 0 = A/ U 0DB2 $ " = ( ' " F2 *

55 #K$$$4 ;)$ &!!"3 % & % K %" K % % 4 %'= 4 #1!4 " ^ a. Q g "^"a " <4" A!%B 4 %""^ 'a < ^<a! < ^! < a " E^1<4a '^$ a 1 " &^&a K ^a % 6. ' % %" " 9 %" % & %((. "^ = a = 7 1' ^% a -(< ^-<4' a - E^' %^% a %.E ^$<a 4^154" a ^@ " a E4. E4 ( ' %= " ''" " ' %= " ''" " E "E4 1"'' " ' 1"'' " 2 % = I 14" ^ a E4 = % 4 = $^ a!" %= 0 ; " ' " " ' )

56 . 4 F %" E^Ua 4^1 a ' %= " ''" "9""< E4 %= " ''" " 4!" %= "" =4!"#$%&&' $ " ' 0 " " ; ' A' = "B2." "" "'' " ' 0 ( ; 9="9 ( " 2 $ %& $ 0' (Q"' (" " ( : 0 "9 5 == = 0""9''" " 2." " "2''6"= 20(( 9'" 9 == = " 2K=( " "9 "2$9 == = " A6"=0 B2 $ 9 "'' < ( " < ( "9 "2$; ( ( A"0 B " 2$9 " +C( = " " 2$ ='< 2$ " 9 == = = 4 " A0 +B2 1' G0 " 9""<4" ' ( "'0"; " <A%<B2"" "9 " " 5 == = ( " 2." " "( ( " 5 == = 0 (" ( " =" =2 $ % & $' " ( " " ( ( '2 " " "9 " ' " " A! 0B2 4 %( T ' ^. "a0 9 " 09'' = " 0" "(9&" "2 %3"9" " ' 9 "E^K "aa& ( 0B2 C

57 19 (;09 = " " " " 09 "9= A! 0B2 $ ( " " ' " 2% " " "" " ( 2$ F FK " " ( " 2 #K$<$ 2 %6;!":N!"3 % & 4 # 1! < -. 1" 9 "' %5 == = " =! " <."=^ (<a %" 4 ^ %a "^"a =^'a 14" ^ a %< ^ a ' "^=a ' ^%= a A.' %&&FB "4 "4 < % = T ' ^. "a = " / E^K "a "9 " " $ = :" " " ' " 2." 9 = ( = ( " 2 $ ; = " ' A' = 22C2B0 " "; ' A' FB2 $ ; $ " ( " A " " 7 0 B2 $ "' 9< " = < "2%";" < " " = " ' < "4(< A ( B C

58 ( "' 9< " 2 $ " (, a0$"a0$=a0=aak" 0B2 ) 2 $ "9 "" 0 "" ( " A60 B2 < " 0' : "9 2 ( $9 3 ( "='0 "'' ( = +5*H ( """ 3 32$9 < " A-= B2. ( 0 ( "" (" = = " = " " < ' "(AAB0B2 $ ""9 ' (= ( A<,( 00 'B(+5*2$9 "" " < 2$("""("9 0 $E"+U=2$ = I =( "' "2 = (9J= E ' E ( ( AAB0B2 $ "9 ' ( "'A)CHBA-=B2 $9 ( <4" " 4" 9 " "9 " 4"= 2 1 E4 " " " "A&%1 R B " &%1606 R 2.<4" ';'.Z " 2 % 9<4" 0 " 4" ( ' 9 " " 9 " 4" " 4"= " 2 9 " ' 45E4% ( E4 %2. " ( 4"`A" R 0B2 =% &1 1 %@O1EE/"3< %N%!/!1CH; "" "!!"3 C

59 $"9 <("9 ( 3, 9 4 "9<4" 2. ( " = " "" 9 " 4" A" R 0B 2 $CH ' AB0 A B09 < AB (AAB0B2 % &' %&7P!!0" $9 ( ( J" > =0' ( '< = > =2 % ( =A" AB0B2 $ %& $ "4 (' ( ""9 "9 2.5( = ( "4(< ( " 0@%/%A " = 5 4B2."( '< : ( " < " " " ' 0 4 0'' " 'AAB0B2. " " ; "9 (" 9'' " ' " 9 : E " " (= 0 " 9 0" 2.''( ; '"9 " "A@( "0CB2 1 " " " 4 (< ( ( 9 2. " E" E 0 0 < < 0 = " 2 $ % &$"!!" $ 9 " ( ( ( " ( " 2"="< 09 C

60 5;( 9 " " 0 9 " ( " " "9 0 " 9= " 2 O $9. ( " " 0" 9( '" 40 = (" == A4 ="4"9 ( "" B2. " ( ' ( " (" = = 0 "' " "9 " " <0" ^ a " " ^!a A 5 <B0 ( = (" = = 0 ( G "9 " "9 " =0 " 4( "9("40 : """9 2 O $ %( " 99 (E4 " "9 0(; 2 (9 " 4"= $9 " 4"= A%16B = = " 9 A' = 22D2B2/" 5 60 " " 2 9%16 " " 9''" = = 0 = <"9 " =2." 9"9% ( " "" "2. 9< 9< " ( = " 9%160 "9 ( ( " 5 6 "9 ; " " 9= 2 19 " 9 '' " < 5 62 $9%16 " "9<4" " " "=< "=<2/"0 " 9 ;( 30 ''""9 ; AAB0B2 (9 " 4"" 4"= $9 " 4"" 4"= A%$16B ' " 4" "2# " E4 : "9 " 4"0 < 9= 2. ( 9 9'' 2.5 '0 " = 0 4 "0 4 0 " 5(0" " ( " 0"(=0 0 " ' 4 ( 39 AAB0 B2. '' ' " 9 0" "' A% ab2 $ " " " 9'' ( 9 " FK2 C

61 9 " 9%$ ' ( ' 4E4%A 4.%B09" 4"`2.' ' " 4.% " < 4 9 " " &5 4 ' 2 $"9' "9 0 ""9 4.% 0 0 " " 9 E" ^ 'a A <B " 4 2 % "9 ' "9 0 " " ( = '' " AAB0B2 #K< * )) 4 %! " % & % %'= %< %" % < % 4. ' <^ a. ' E^.'"a. ' "^ ' a $ <'^. ( a. ^.a ` E^`"a " E^a! " E^- '(^@ 'a E"^ a "^%5 "^1 a E^& a & "^% "a 7 ^% a ' ^% a " E^ a " E^- =a - E"^-<a %" "<^&= a % U /^ "a " $"^1=a %" " 9 1' ^% a (4 $9 4 ( " "" "" " "4" "9 2. =b"9, $ "9 ' (.Z2"' G =b09 " " ' (.Z2% " ( =" = " '' " <0" E< E ^ '<a2.9 " 9 4 " - ( ( " " = 2. ( ' CC

62 " 9 ( ".Z2 $ ( " 9 0 = " '2 % ( =0 ' ( < ( "9 A!U 0B2. "9, $9 "' G 0( " 9 ( ".Z2 $.Z "" < 0 " " < A! 0 B2." " < ".Z0( = E3 2 " 9 " 9 ( "9.ZC,.Z%0.Z.*0.Z1D.Z%A%&!AB2B2" ( ".ZC09 : = " " " A".ZCB "'' 2( " ( "9 0" ( "2 $9"".ZC( " ' 0 " " 0" ( ; < :" '' " 2.9 <" 2 "".Z %0 9 ( " "9 < " 0 : ( ' " &5 455 E5A&%7BA-=B2! B2! 9 0( "9 0 0 " 4 ( = = 2= 9 ( " &5 455E5 = =" 0"<("" <' 2A! 0B2 94 2& 7!!9" $9 " "<4( <4( = ("< " 2$ " " " " FK2 CD

63 #K<$ % ;'3 % 4 ) %" 4 4^%a A!U 0B. ' ^ =a.e< E^- =a 1 ^1a ' ^ a0(' ^# a0 <4' ^<a 6 ^1 a %.E ^$<a 4^F a A%&!AB0 B.* ="^&(a = ^%( " a % 1D.' F8Q7; ;3 - ^- a0 ' ^4a! ^%<a + 2 $ ( " " 4 0 " 9 = " 9 ; " " 2 $ " " ( 3( "9 " " 3 A& ( 0 B2." " " 3"9 ( G< 5 0 " ( = 30 " 9%&&F2 82; # " '"9 49 " ( 0 = 2 G" 3"""D0=IU= "9 =" '" ( A*H""4"( 0CH"( C H"9 ( B " 9 =" ( 2 $ 9 '< " < " " =IU=0 ' ( ""9' E '> A 40+B ( " ( '' ' '>2 "; ( E '2 $ ( ( ; "4 0 ( ( = ( " : = " 9'' =2! ( = ( 2$ C+

64 ( 030" ( " "9 " 0 9 ''9 ;( ( " " ""9< "9 " A.=" ""7 "" "7 0B2 82. ' E2 0 0'"9''' " " < 2.9"E4 "4.Z%0.Z.Z.) < " AB" '"' 94 94' "" ( " = "' (Q" A1 (40 *B2! = ' "< "9 " 30 94' 94 " 9'' "E4 " 2.''" "9 ""< ='' ">0 ='' " " 0 " ""2$9 "" "C DH" =" : 3"=''" 2 % ; " 0 < " ( ""9 " " 2 $ " =4 5.Z%0 " " ".Z%0 = " " " 9'' " " A6 "0B2 82 == " ( ( 9 = d ' ^. "aa70b2 1< 4" == 0 == A1 2 == A = 20" ""C=" d ' ( "== 2. " ' " (= ( = d ' = d ' "==2'" 9 == = 0 9& " d ' 2 $ 9 "' " 9 == = " 0 " ( " "0 " "' " 9& 9 "' " ' " " d ' 2 8 = 20 == "' "4 0 " d ' A8 =0B2! %" " 20 *0 " " (= == d ' " G" d ' " 3 " G" == 2 < 0 ' 9& d ' 2 $ " "" 9&0 " == = 0 9 "" d ' 2.; < (== 2% "'' "== 0 59 '; A70B2 C*

65 / " 0"9 " "9' ( " " 2 " 0"9 ( "9 ( 0 < ( <"& ( A%&&FB=" ""7 9"" " 7 A.=" "" 7 "" "7 0B2 C)

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

67 O. "0 ' G " = " " ' 0 " 9 :" 9 " ' "9 ( "9 " ' 2$ "( = ' ( " ' 0 = 2 $ 0" " 0' (Q" ' (0 " ( '0 5 == = 0 d ' 0 " <0 " " " ( ' 2 03 " 9 ( " " 2. : J" > = "" "'<= > = E 2 O 0"9 "( " " " " "! " K " ( " 2% 3 " "' '"' ( 2 O "9 " 2 $9 :3" ( "'2." ; " " 0 9 "; " ( " " $ "( ;(= " '''" " ""( 2. " ' ' (0 " " = 2. ' " = "9 " ' "9 ( "9 2 & " "( " "9' " ( " <("0"" " " 2 D

68 233$4$ #K<$$ 2:4(3EE0" < 82 C 4 C 7 C, C 7) C C 6 6 C) ) * C 0 ' =.< D* +0C )0 + 0D ' =. 4 C DD +D ' ' = K 0* 0 C )) *0) 0 ' * C & " ( +* C C+ & " K ( D+0D 0) * ' 0C K( 0C * 0D + *0 & " ' C C + & " <= E ' ' ' ' = Z ) +* D* + ) " ' K4. + )*) * C " ' E D ) *+ & " ' " = D

69 7 E )C CC D*C0 0 = " ' 2 K ) + C + C ' ' = / " ) *C DC * 0 = ' = *D0) C0 ) 0) +D 0C ' = $ ( C + * C & " 0 " CC D0* 0* C D0 0 ' D

70 % 5674"!-" D

71 233$4$& #K$K % 2&:N!" % = 1 0' 06 0' 0!<4' 0 (' 2 % = 5'.<01<<40" 0 " 0! < 0& "0 0 4 E0" %5' Q"2 % ( < % (01 "0" (0$ ("0 &' (0& ( "0 (0 (0 ("0Y 0Y"("2 % 5'< %" ( 0%" '0<0 E"0 E0 ` E0! "0&' Q0 4 E "0' 0' 40 ' "0 '2! " "= %"0%" 0.0! 4" 0! " = 4 "0 ' 0 0" %"( Q0%" 0/ 0. E ' 0 E"0 $ =0 < 0 E"0 Q0= "0E0 0 "0 2! " " % 0-0@ E0 0 0 ' "4=4 2! " "( %0% U4.+0%5 "=0%5 660 %E "00@ 0 $'"0! 0! < 0 =0= '0 <"0 Q"0 <'0K % " " =2 DC

72 233$4$' #KK)) '? @= 6 =4! ; = % = %5 == = %4 " 3 % =< %" % %4 /E" E %= < & % $ " " DD

73 %' Q" % Q".Q" %". ' < 6 4Q" %'= % %( < $ < ' " /" % = % < 6 < $ - D+

74 0"' ""0<" "I" " 2 0("0<" "< "I 2 9< "(< " 9 "" I "4 2 D*

75 $ " <" ,,IIddd 'I' "I#5.6%&IKh I(h(I I hi%#fh 2"'2A. )(B2 5 ) ;3 % ( ( " 2 1,,IIddd2 '(2'I1 5555"22A. ( B2 5 3 $ ( " 9 2 1,,IIddd2 "2'I (5"55 5 *D2 N^2A. (B2 5&3 2 1,,IIddd2 =2dU2I 22A. )(B "2( " ""L = M2 1,,IIddd2 2'I'I"I&# 2"' A. B "3 $ ""' 2 1,,IIddd2 2'I'II5555 ""'5 2 A. (B "3 $ " 2 1,,IIddd2 2'I'II5 H.H%)" 52A. (B "2 % ,,IIddd2 2'I"<22A. B "2 1 " 2 ( " " " = 2 1,,IIddd2 2'I'I"I.%C2"'2 A. B )"2. " 2 1,,IIddd2 2'I.7#%$I2A. B "3 % ' G 2 1,,IIddd2 2'I1I%& "'2 A. B2 D)

76 5674"3 % 4 " ( " " - 2 1,,II 2 2'I5'I5.55IK5"5 " "5 45" A. )(B2 5674"3 / = " " " ( = " 2 1,,II 2 2'I( I hi =I= I I C+))D' D**" )D* 2"'2A. *B2 5674"2 " 42 1,,II 2 2'I15 I 5" I 5 " 554IA''BI2A. B2 5674"3 2 1,,II 2 2'I( I hi =I= I IDD)DD"*C+ ) " C D2"'2A. D%(B2 5674"2 " 5 "X' 2) ( 2 1,,II 2 2'I5'I5"5' 55"5 ' I 5" 55 55"5 ' IH* = =H)I'5-2A. D (B2 5674)"3 " " 2 1,,II 2 2'I( I hi =I= I I D+"D)'"'CC C +)2"'2A. 8 (B2 5 4 =;? "2 $ ' 2 1,,IIddd25 2'I IhI++I%C+I$. '2"'2 A. %V B2 5 4 =;? "3 $ 2 1,,IIddd25 2'I IhI++I%C+I$ 2"'2 A. %V B2 573 " = 9''2 6 "2 1,IIddd2 2"' 2 2'I' "I$515 -%&.I%I+h%hh I h"h= "Ih''h2"'2 A. 3 (B2 5 2 ( = " 2 1,,IIddd2 2'I'5"5 I"I(5'55(5 'I(555 = "I(5 5 =5 " 22A. *B2 +

77 ,H A#() 4# 6; =A2 ' 4 d U " '.Z%5 " "4 "4,"dE " " ''28. 2D8SDADB,C5D2,:(:(5A453@ ' "",'""' (" N! S*CAB,)5D2,; (;(3 D3 AH%L3 A( (R,%73= 3 " (== "4C%4 (4' = "= 4 '= '2/=!".2+8SCAB,D*5 D)2, %33 K " 9, '' " " 4" S "8(S))2,3, 3:3 ( " =" " - 2 1,,IIddd2 5 2=(2'I!@I"'I h/= "h. = 2"'2A. *(B2, 2 $,? " " 2"?"1 0#( "S 2,& 53, A33, 53 %& A3=3::3: (%)A3( >3= (3:3#H:3<% 43$ ' ";" " EX' - 2%(" " 2&(S )AB,52,,3 " "", 4 S"S2,;42$X(2"$$ ""X0! "X6 0 $4S))02C2, <3( %#3, 2 8 " ' 2. " & " R1 2&(S*ACB,*5CD2 %;2=34=A2/ '" ' 2%(" " 2 ))C8SADB,C*5C+2 1) 12 $9<= " 2 1,,IIddd2 2I5 5 I5<=5"5 2 A. &( B2 6 $ ) 18 6$8" "2 7 " N1,,IIddd2"5 2III+I55"5 I2 A. C B2 +

78 6 $ ) 18 "3 $ " " - 0 < "2 1,,IIddd2 2=(2'I!@I"'I h"h"h h%$%2"'2 A. C B2 &0 5521,,IIddd2=' 2=(2'2 A. B2 > % 2 $ "" 2 1,,II4 d 2'2'I4I4 I H H 2"'2 A. 8 (B2 3R63$ < 2. "&"1 2 -SDAB,5C2 A3:;=2. ' 0 0,' ( S ""8 S2 :% >3, 53 8 NNN >3 8% 3 = " 2 1,,IIddd2'2 I 'I.I=I2"'2A. *B2 :; 52 $ A= " B2 % 2 * 8S +A+CB,C+5C)2 :4(2$9 S"1- S))C2 : 43 3 = );(3 4 2 " = = ( ( ` " 9 " 3" 2% - G "9% " 2)S*AB,*)+5*))2 :' 72 $ 4 "=', $ "= X 2 1,,II=2(52'I "I)I1=hhhhh(h*2"'2 A. - (B2 :N2@"" " S "2,! S2 : 53 $ 2 $ 2 1,,II< 25 2I =I45 = 5"I2A. *(B2 :% A3?3, A2 $9 94", (2 8 " " " 2! SAB,) "9 21,,IIddd2 ' 2'I(55 ( I IN"h ^D*2A. &(B2 +

79 8 S7 72 $ 3 9, $9 " 5'' 2 1,,IIddd2(2I 2"'2 A. (B2 8&G 5!!I0.g1.i&6%&0 +21, ddd2 "2'2 A. B (3( " < 2 (- G " $ 2 ))*8S))*AB,*)5) ", " " < 2 1,,IIddd2<2=I I5"5"5 <5I2A. ) B2 B= 7 2. =2 1,,II'2 "2I"2'I'dUI*+*+jh52A. B2 = " " 2 1,,IIddd2232'I4I I4I22 A. C B2 %NN(3 =%:T < :3 4,H,3 ;?% 2.' ' 4 "= d"( = ""4" &5.2%8.&2! S)+AB,C+52 ;?:) ?#; 43?3 > 63 =% A3?3 U 43?3 < %3 $, 4= =2 % "X"=2D! SD+AB,C5C ( "9 ( 3 " ( " 2 % 2*&(S+A+)B,+5* # = 7 7N? 42 '' ' =4"U = < 2%.<2D%SAB,C)*5DC2 )2 $ '2 1,,IIddd2' '2'I I5"5<I5'5*+)C55*5 2A. (B2 % $3 < ( 2 1,,IIddd2 2'I(II+II < (5 h*)2a. B2 821 ',. ", " " 2 "0$ (S2 +

80 2 $ ' " 3 " '2 1,,IIddd2'2'I2 A. *(B2 (;:3 6; 3 = 73 =,3 = :3, ( ' '# " = 3" "( = =4 " ' #(4 6 '!" = "%1"2CS*AB,C5*2 (3$9 31,,IIddd2= "2I 22A. 3 (B2 (:27 "N"?"1 "S2 (;8N34A3# NHD3$=3=, " " " " " " <2 1,,II <2'2'I II1I=322 A. ) (B2 ( :A;4 H NA7%(U%))AA 3' (4 ' 4 C % ' ' = " ' = ' %=S+AB,5)2 ( 3 4 4%,3,30. ''! ", % (d ' <%." "= = 42% ' "=42 C8SCADB,D5DD2 ( =H '= < " " = " "4U 2 1,,II=)2I"<2N^ 2A. *B2 V 73 7 >3 4W #3 :%&; 3 '' ' '' E U 4(2/8. 28 S)AB,C)5D2 3 % 4?3 4%?7%% 43 '' ' =8 " 6 < %(4 "$"'64 2/ 2SAB, )5C2 43A3=3UU3U3( :3A3'''= '3 "="2<1=! <2! S+AB,D+5*D2 :3 =3 =H 3 83 DR 3 H :3 # d '< " '' (2 % %=.2)*) %SAB,+i+*2 3=2. " -, ' 9 2. "" 2SD,5)2 +

81 L L,& (, 5 =3 8X d A64' B,"= " 2/8. 2 SCAB,)iCD2 H436 43DRL37H3D3LHD3>H435 D2 4 '' ' C.) %(4 K2 /2 /2/2*-S+AB,D52 3 % 53 $ "9 ( - 2 $! " 28S)A+5*B,C*5D2,27 53N$9 S "#-S2 3e(0KS"#$ %S)CC2 25, -" " "2 '0="'"'(421,,IIddd2"< 2=I2A. 8 (B2 A4 = $, 4 #5 2 '' ' = = ' U " " 28.&2SCC,**5**D2 $"3<(,%'' S"/!= S $"3., " 2 1, ddd222'2a. *B2 $"3 $ L=M = " " 2 1,,II (2(2I I+2/**DI55=5 =555"5" 22A. (B2 $ &2/ =, ( " 2 1, ddd222 2A. *B2 $ % H2-5 " N 1,,IIddd25 2'I' 55"55I(I2 A. (B2 $,473 ;" " =,. """ N " " " = E '2 1,,IIddd22I5 = I 5"5'I 555= ^+22A. - (B2 +C

82 AR D3 7 X $3!" ' = ' 3 " d ( "=2&82+SD,2 A&8330' 5"9 N 4"2. """ 2)S,)5)+2 AK3UD34RU3735 5A),::H: % > 4% 5R A2 '' ' 8X d " == U " "4 ' d ' 4 32 / 8. 2! 4SC+ACB,C)5C))2 D 43 $, =0 2 "?" 1 "& 4S)2 (A :84H(, 31 "9'' 2=#=2&(SAB,+)5+) ! " 2 1,,IIddd22=I I 5" 52A. *(B2 3%; "3)++X "" "3)+C " " " =2 1,,IIddd2=' 2=(2'I ''<2"N"<^$@FD+*+k" < ^2A. (B2 %"3@"U',= 2 &(SC,D5D2 %"2$ 28 S)DA+B,*52 %"2$'<= 5> =2&(S),*2 % 2$ " 2%SC,5D2 A3 < A?73( 3 ),3 $9(" = 2 1, 22=I II)Ih5hh2"'2A. (B2 ;G&:% A36;2L3 =37 B?7&(, N <N 70! " " "9= $ ("! "2-SAB,+5+)2 43 5R U A3 7:3 3 < =3( 3 =%,3 7%:3: 5 (3 :2 '' '. 48 U ' l5$ % 'd= %" 2%%=.2)84TCA+B,+Ci+2 +D

83 75, = E" = " 2$030 =21,,II2I'I"I 5555 =N^2 A. ) ( B2 4 % 52? " 4 C " " ( 9''2"?"1 "$ S $ " 2 " 2. 4S2 4 % 62 ", " 2 "?"1 "& 4S*2 4(;=3(H:3823< 43& "T0& *S))D2 4H =?( 83 5 L3, % 3 :3 i< 2?"4C2 =/=2S)A)B,D)D & 6 % 7%H :2! 3 ' = ' 3, <40 =<4 " 4 4(2 4 C% (42 -" " <=42! SC,+CD5+D2 4 2 $ ' :," '0 " 2. "&"1 2! SDAB,C52 4)) 2 %.( 64 ' / /d=0 6 "U ' /d=, 0=40! U2"T$Z5K.6K =@6k.S) )G 2 "" " ', " " ' G 2 1,,II =2=(2'I 5= 5"50*+)2 A. (B2 4P=27 <"'' J=" (N. " " 2SD,C5D2 4 2 < " ( " " < " 92 "?" 1 K ". S )2 443&52 =, S "! S %$3A$3,A?2'"3" < " 2 =K <2! SDACB,)5C2 ++

84 6; $ " 2 "?"1 "@S2 6,2 $, "0 -. "&"1 2&(S+ACB,5)2 >; )+ 23 $ "9-2 1,,IIddd2'"2'I'""(I(I"I I22 A. %(B2 >=3, %3 2''(( = 4 " 28. 2SD,*+5)2 >AU36,37 N8362 =, U N82& 2<2&2))D&(SCCAB,C52 > 43:2$ '," 2! "! ""9?"S2 =%2 / 2 1,,IIddd2 2III%h22 A. D B2 =35?52 ;" = =; 2% 28 SCACB,C5D2 = "3-< " ' " < '2 ( 2 SA*B,*2 ="3, ("< " 2(2 SA+B,D+5D+)2 = 3 1, ddd2 ==2'2 A. B2?U3U?X3:(?A3X%X?L3R#3L?72! '@= " d1=2.1=! 2&(SA)B,**5*2 A24 S"$ (SC2 A3:3<A343X%A353:3(D37 ;43U433, 3530 '' '= ' 3 ' '( 0 ( "0 "( 6!@5.%" 0%0)))! 4SAB,*2 #0 $ " " 2 1,,IIddd2 2 I'I'5'I( 5I " 5" 2A. *B2 +*

85 343 ",0""9 ; 2 " S))2 63# (3: 53%82'''= '"= 5=4 < 6`52$'01S+DAB, )52 7%RNB3$A% =38,:3(3%D3,34(34 52 ' '"U (= '3"2/8. 2 DSDAB,*C5)2 7%RH 53 4HN,2 ' d "( 5 52//4.2! S)AB,+i+C2 7PD38=2$9 ", "9 " G P(! " 2CSD,2 7 53( 83<; 3 U 8:3 43 ) A53 8H A:3 U A2 '' ' 44= (4 "5 (4, """5" 2+8 S)AB,*5)2 7 A3?3 7%?D % <30 - (Q" 0 - G 2! SD)AB,+*5)2 7 H;Y 53# 3 =% DA3:Y X3 =ZY A3 >$2/ ''< 5,. ("4'' ' 0 0E ""=4 ""2 % 2! SDAB,++5**2 7 )3 1,,IIddd2 2=I''22A. (B2 # U& 0(;3@" 5S"T`d- S2 ##3 6; = = " 3 = 4 " '%/ U2/3 ' =40 S+ACB,+*5+D2 #% 4 3 " ( 3 " 2!" $8 S,D2 ##3 73 D ", <=4 ". =4S " &d84s+2 +)

86 B ) ) 3 " ( " 2 1,,IIddd232=I1' 2 <N"^k"^Dk("^*2 A. (B2 <43=3A52" S"$ (SC2 < A %( "" 5 " ' ''(" "R,% 4 ( X "" "" X 5 "" '2 2))DSCAB,)5D2 <2! " ', '2 1, ddd2(" 2'I I'5 *22A. B2 U7:( A3:;43U2'''@ ' "( =8 U' S AB,D5+2 U3>63=42''" 4 "= " 2.1=! 2&(SA)B,++*5)2 L A?43 7 3, *2 ". (, "= "2 2%=SDAB,iC2 : X3 D; W D[333\ H% :2 ( U ' " 4( " '' ' " " ' = ' 32/ 8. 2SCAB,))5+2 X%(3 U L3 X% L3 U K3 A3 D3 3%5. %( ' = 55@ /. " " 42.!!"2 -SAB,D5+D2 *

87 6 $ " " - 4" * : 2. ' ("2! 55 = 9'' " N. "' =", - 0 9'' 9= 2 $ ( ( "9 " ( ; "4 2%0 (;""' 9''" 9''" " <0" "" ( ; = ( 2 " " " '"9' 9 (" 9" " 2!,0 0 0 " 0.ZC0"02 *

88 78486#:8(5$86 8 " :""033, :9<9" " " = '" =2 :9<0" 9 ;" 0 ' (" = (=0 ="90" "" 2 :3 0"(( " "= 0" ' >' (" 2 9 "3'" 2 3("9 "' 3 = =2 *