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9 A D/,)2)3/,0 Abréviations -9 D./2/,+,-./-/->52,)+-2-3 D)2,-4+.,)-/ D)9-,0/:-/2)+)9+5 D5.9:55/2 D50.62.> 025 D50.6.:,2.> 025 DC*+,/0-./-/,+2+F/-// 78 D /3'3+4-,0->*5-=-70->*5-=-32:,*@C0-.5.C02.+8 D /,+5:G-/ D >+-*+)0.//2/),-;: D-;:-3)*@5.+2@-3-/ D)/-/-,92,)+-//2.>>:/:,-+ D+00-./+,)+-5>.C// D.5C>)+0@-/2,-./ D*+00-./-/,+2+F/-// D./2,-./.>9-+

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11

12 Toutes les lettres ne sauraient trouver les mots qu'il faut Tous les mots ne sauraient exprimer la gratitude, l'amour, le respect, la reconnaissance Aussi, c'est tout simplement que

13 Dédicaces!" #$$ $% " " %""!&'%()# ' " ** ")+$' '#$

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22 , , 25*, - 5! $+ ")+ )+ 52) Remerciements 3#"+)"'7 )& 3 $ " $ ") 3#)C ) "$

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27

28 Introduction!" #!$ " # %&%$!!'()* +!$ $ %#%#%# ',)* " % " & ' ) % '-)$(."-./$# -./$##'0)* $ 1 %% 2*,. $ $ #&"3%2'3)4"!$ & # % #5'0)*

29 Introduction! %2 #%2'6)*#!!! # 7 '8$ 9)* % # %#':$;)*!$ #!! # (.. 7!,..:,..; 3 % $ " #$ #$ #$ #$ %#!! # # *

30 <==>5

31 Rappels 3>1< 3>1<&> > >=3<+> A3> % %& &C % %D'(.)*% 7! $%%$# #!A * %D % % C* > 7 E % $ # E % $ 4"!'(()* A3> # $!! # % ' >1 )$* >1 % * >! $ 7 % 2 # *>%%$ ## %#%'(()*

32 Rappels!$ 7 # # >1!,."-./!* 7 $ F=G! >1 * >1! A3> #%# 7%*!* * "! #%* E % 7 % # #%!'(()* E E!!! #! A3>$ % >1 %! H'?I&H) 7% >1 *

33 Rappels! J!!* 0 K! $ '(()* %& %D$!!$&C % " E &! % C F% %DG '(.)* &=3@5=<3?>><1>?> >>A&5=<> 5=<> <&=>><> <><?> <?>=<3?>><5>+> =<3?>><5>+> >=3<&< 3> % * % 7 %%%'*()*!" * $!!%!% %& %#'(,)*!! % %D* # 3% 2 %2! '(-)* #

34 Rappels! %%"!%$<$ "! $% '(()*!%#A3>$! #% %!L $ M# " % " # "!%*!!E %E$ 08'(0)* A&I<11<>>5=< >55&<< 3N> $ "!! J"! * O 'IP$ ($ 8)! # " # %%#'(,$(6)* # O$ % % % '(.)*

35 Rappels $! %* >!%$ % C IP$(C=5%"!'(8)* &<><><A<>>3>1< <><><A<>>3>1<&> > >=3<+>>3 >3 # O A3> %$ "(#K#! IP* > $ "! Q %#" %&%#'(8)L!$ % 2 # L L! IP$ ($! '(9)*!! $ A3>* < R #! - M#J" * - J"!!%D*

36 Rappels # R % 4 #'(8$(:)$ R " #! * '5 )! $" 4'= )"'=<1)5 S '=<1&= )'(TM )* >= $M * <&" $!! K! == '(;)* < # $ % 4 " % $ %###!* C$ "! *! %#$! % 4$ " " '(8)* %#! # & %D $! $ $!#$C$#% C$! *

37 5>=55 Rappels >%!'R $% ) '$ % # M)* #"$! % # " $ # % % %#IP$($! * 5$! % %# '% $!$ % )$ # " %$!%%!$#!!',.)* % # % " %E$! C %E! %$ $ # % %# <* %E #O*=$ &O$#$$ ($,

38 Rappels =?=',($,,)$IP$($,$(,$(: & * % $! #* 7 " $ #"!* O!! &'(.$ U% P) # $!# 8 %V# "# ',-)*

39 Rappels!"#$%& '( ) * + %-(. ),, I(=%% =%% '(.)*

40 Rappels &>>1>5>=5>> 3<?><?5+>5 >3><=>+>5 >3><=>+>5 <&<?5 +> $ $ #! *!# $"$ " %$ # Q % ',0)* # %2 $ # %!$7!* M7* &#%* &#!C' WA2O)* %%*!!',$,6)* #$!!#!# $!*!*

41 Rappels 5!*!&* =! * >$"% $"##-./ "* # # " # #"#',8)*$$!# "#* '#$W A2O)!*1%$!$ #$ "(../%2',9)* A&<?5 =<< +> = *>C#* # # #$ %## %*

42 Rappels 1"=C$# # # % 4* 4',)* &5<>?><?5+>>=5>> 3<?> 1A # * %%# ',:$,;)*! =$R '-.$-()* * # = C $ 7 #$%* >!%$ # $ % %!=$':$-,)* # % $ % C $!!$ # " %'--)*

43 Rappels # % " # '-0$-6)*!!"#$ %!! # %!6./"6/'-6)* $! % # = $= ';(/)';(/) "#$ C C #'-8)* % %% % %2 7! *! %# # " $!$ = # "'-9)* %$!=E #K#C%2 " 0:% % '-:)* > % %#$ #! C *!$$"!%#L- $<=< 3>$?5$1=1$! % *<%$! #'-;)*

44 Rappels <=< 3>! # IX '0.)*!%#%!$!7!%#'0()* D&%D!"!'0,$0-$00$06)#!! "%% 2 %2 # '08$ 09)* %2 %! " % " #* C! 7#! 0 7 '0:$ 0;$ 6.)* $ %! C #'6($ 6,) C! D %2 % '0:)$ $!! %'6-)*! " %# *! #! $ %# % %MM!!! * &'60)*

45 Rappels "!! " $!$ $! $& # F U G % '66)*"#%# #!'68) %-...TY&'69$6:)* # %$ #!!%#'6;)*

46 =<>5Z1>3>5

47 &=<>5 =<>5 Patients et méthodes <&=>5><>>> =>5><>>>!#!!#*> (..'4(0)%7!,..:,..; '1A )* "%! 3A 3 * A& >>5 5 5!"?" * 5! $%%'[6 T-)!6./%* %* 4"(0* & >>5>\ 5! 4%"(0 # #! *

48 Patients et méthodes %!$#* '8.)* * &1>3>5 1>3>5 <&>I>5=<<1>>5>>5 >>5 " %#')* %# %# >4* I I!C!M3* %%#!* % * (,* > > *

49 Patients et méthodes %##!* %* O'8()* &* # # #! # " $! %%*>!!* %# ";.3'8,)*! "-:]* #')%$ $ 4$ %$ ^!?U * %* $C!!* % " 8%!

50 Patients et méthodes $#### %,"-%'80)L 8 %!# %%#$ $8%! #!*7!!&% $ C 7!!!!* # ## # =" "%E*!%! %* $ = $ % T$ %T%T* #!! %% $#!*

51 Patients et méthodes %# %#% % %$! $ # " % * > % % &% * >"%E%% *! %! %* K % 7! 7" %* >! >!% % > $! " %E!* >!$ #!! C $!!!* #!?5 ( $,!$ -! $ 0 6'86)*

52 A&1>3?>?>5<5+> 5<5+> Patients et méthodes #"1>*!"!,&!!*!#! $!#! *! C * #! 5=55 ((*6* = %# $ $ '5)!' )* "! # &!!*!#!" %&,'I%#%#" 6/)*!#!"&*_.$.6 ' ;6/)* &!#! # F!! G!!! " _.$.6!* <! $!! 7! ".$.6! 7#" # #!7".$.6*

53 >5<5

54 Résultats &>5 =>5>5<5 <& << >5+>5>1?<=3+>5 (&< < 4-:$09!C(0" ;0' -;&0;$-) Nombre de patients Age des patients I(4* 4*

55 Résultats,&5 8:%'8:/) -, '-,/) ",$(,'*,)* 68% 32% Hommes Femmes I, * * -& I-* *

56 Résultats 0&<!%2,9/* M* < < * * < ='/) &4 (: (: &A % ; ; &1 9 9 & 6 6 & 9 9 &< 8 8 &, 0 0 &%! - - &M**3,, &1A%K ( ( &%# 0 0 &3% ( ( &.. &< -: -:

57 Résultats 6&=!!,; ',;/)! < %E* 9('9(/)!* 71% 29% Domicile Autre hôpital I0=! =!* * A&>>5 +>5>5=<>5 (&5?U'? 5) $?U (($(8`-$.0!C-"(6-9'9/)!!? 5"(6* - 99'99/)!? 5:(0* - (8'(;$:./)!? 5"(.* - 6'6/)!? 5"-"*

58 Résultats,&#" 9-'9-/)##* 8( '8(//) %# ';-$(/)!! # ' )* :8':8/)!!* -& #!%2,;" " 5* 5* 5 3 % < = : - 0 (- ='/) 8 8 : - 0 (-

59 Résultats 0&! #!!$-8 '-8/)!"*!!C"!* 6&='=< ='=<3 3) # '=<5) (,-$:6 `,8$99 3!C0.,(.3* # '=<) 9.$0( ` (8$0( 3!C,.X((.3* %%2:"- %* 8&'] ) -:$;0`.$;9]!C -9"0(] * :8 ':8/) "! "-:] * 9&= = %2,6',6/)"

60 Résultats =%2 =%2* * = ='/) < A %& %% a 8 ; 6 0 ( 8 ; 6 0 ( :&> > %2:':/)* " %2 '(/) %2-'-/)* &>>5A?+>5>A< >?+>5 (& (9:::$,,`:.0.$89'?AT - )!C(6.."0(-..'?AT - )* M#?A* #?A*?A'TY) ='/) [(... b(... :( (; :( (;

61 Résultats (-8$.9`8$.(#T!C ((."(6;#T* M #* * '#T) _(-6 (-6X(06 [(06,- 9( 8 ='/),- 9( 9( =(6-$,6`(,,$89T!C.$8"8(.T* M # =* ='T) ='/) [8 :, :, M #* 'T) 'T) ='/) [.$6 6 6

62 Résultats,&#% #%&% % &<# M # * < = \%%# --,;,: (. ='/) --,;,: (. & %(-0.$69`,...TY!C 8"98..TY!=98/* \ \ #%* %* > T - c8x(..c c(..&6..c c6..&(...c [(... -9,- ; -( (. ='/) -9,- ; -( (.

63 Résultats &A%?%?% %.$,:`.$,;T!C." ($6T%T.$,6`.$,9* \ #%*?%'T) 'T). _.$-.$-X.$6,6,: (; ='/),6,: (; =% %,$,.T! C.$,(":$98T* \ #%* =%'T).$6X.$96.$96X($6 d($6,, (0 09 ='/),, (0 09

64 &A A Résultats 0,'0,/)* (;'(;/)*!-;'-;/)* # 6 * %%! "#* = *,,#"?* ;#* %! \ =# =# * *? =# 1#A 1# 5#H&%# 1 5%# 5,, : ( 6 0 ( ( ='/),, : ( 6 0 ( (

65 Résultats & << >5+>5<?+>5 (&1 1%29:'9:/)$;./ '9.)!*> \ ##* e 3 3% < & < & % >%,, (. ; 9 ( ; 0,: ='/),, (. ; 9 ( ; 0,:,&1 1 1%2(('((/) * >

66 Résultats \M M #1* ='/) 0-0 -&% "%% %269'69/)* >%%2(8'(8/) #%2-'-/)* \M #%* =% < (8 - -: ='/) (8 - -:

67 Résultats >&>>5 >>53><=>+> 3><=>+>5>> >>=5>> 3<?>>><1< (&# # &## ## 1 \M \M1* 1* 1 < M? 12 #,..&-..TOT7 9.&(..TOT7 6.TOT7 -TOT7 ($6T7 5%%#%# 56% 19% 4% 9% 2% 6% 1% 3% C3G seule C3G + Métronidazole C3G + Métronidazole + Gentamycine Pénicilline seule C3G + Vancomycine C3G + Gentamycine C3G + Pénicilline antibacillaire I6<% <%#* #*

68 Résultats & % % " % % " %E %* > $ %2 #$ 7 %'\M)* # ($-,%! C.$6%"0%* \M"%* "%* & & & % % % '% %) '%) ) ' '%) %) 1 98$89`(.($6, ($-,`.$9( ($,`.$9. 1 (.$6.$ %(0$97'5S(($6)* (, 7 '5S6$() " #$ (($, 7 '5S6$,) " #$ (, 7 '5S6$-) " #,9 7 '5S(:$6) " %#*

69 &<% &% Résultats,6 $ % (,;$:8%'5S(60$;8) %($6:%'5S.$;()*,&% % -( '-(/) K %*,( " #$6"#A$0(" #* %2 %".$(6TWT8%07* -&!!!%206'06/)* M<8$6`.$67* 0&<%# %')0*!#.$;/ %2(.*!!') (9 * % # %2(. 6! $- $( ( *

70 I&5>>M 5>>M Résultats (&>!"!" 0-/*?5 -'5S($6)*0,/!!!!?506* " # -($:/'9,, )$ " # -9$6/'- ; ) 6./ ', 0)!* " #!!* "%#* (6#"%* 6%$-%$0- *,&,8',8/)!! % - %28'8/)* - %%%2(.'(./)* - <M %#%28'8/)* -!%2('(/)* -!%2-'-/)* -!%2,',/)*

71 -&7 7 Résultats 76$;7'5S0$;9)!C.$67,97* > $!-$9:7'5S0$,8)* &>><<@ >><<@+>>I< +>>I< >5=5+>5 <&<<@5>M<>> <<@5>M<>> (&5 =$-.%(-$!-:(;!!*!*,&< < 4!!-:$,,`(:$(,$%2$ -:$:.`(8$96*,! 'S.$-,)* ! 'S.$.(-)$! 77'S.$-.)* -&! -('60$-/)!! $ -. '90$0/)*

72 Résultats \M!!!!* 5!! = 'S69) 'S0-) < - - 5, : ; 5 %& 9, 5 1 6, 5,, 5 3%. ( 5 M**3 ( ( 5, ( - 5 <5,8 (, 5 'S.$.8;)'S.$.9-) "* 0&= # &?U?U?U %2!! (,$,: `($;8 %2 $;$89`-$66* 'S.$..()*?U "! "

73 Résultats & (.!!!(9 %2 *! 'S.$.()* & :!!'(0$.-/),6'6:$(-/)* #'S.$69)* &!,(!! '-8$:0/)! (6 '-0$::/)*!'S.$0;)* & =<5 (,;$,( ` (8$-8 3!!((8$90`-6$,-3* =<86$((`(-$(03!! 86$((`(:$:(3*!! % '(() *%!'S.$.,)*

74 Résultats & > #!! '-:$:0 `.$;,] -;$.9`($.-] )* & (.!!! (6 *,! 'S.$68)* %&>,'0$86/)%26 ':$99/)%2!!*!'S.$6;)* 0 '0/) %# $!'S.$:()*

75 Résultats \\ \ %##* M 5!! = 'S69) 'S0-) < -:$,,`(:$(, -:$:`(8$96 5 5'3TI) -:T(; -.T(- 5 -('60$-/) -.'90$0/) 5?U') (-$6':&(6) (,'-&(6).$..('5) < (.'(9$6/) (9'-;$6/).$.('5) 5 :'(0$-/),6'6:$(/) 5!,('-8$:0/) (6'-0$::/) 5 >%. ((.$.,'5) '] ) -:$:0`.$;, -;$.9`($.- 5 = (. (6 5 = 6':$99/),'0$86/) 5

76 Résultats 6&< # # # # \\ # #* M 5!! = 'S69) 'S0-) '#T) (-8$:0`6$0( (-6$.0`8$80 5?A'T - ) (90;,$:(`:696 (:0(,$-,`9--:$0 5 ='T) (0-$:;`((($-8 (86$80`(-8$8. 5 %'T - ) (:(6$88`,9.,$.( 9(.$9;`(898$66.$.,'5) <%'5) 'T)?%') 'T),$.9'($-8) ($:6'.$-&:$6) 5.$(;'.&6$6).$,-'.&6) 5?,8'06$8(/) (8'-9$,./) 5

77 Résultats #* # "! " # $ % 'S.$...-)$! #'=S.$9-)$ # 'S.$:;)$ % 'S.$.8)$!! 'S.$;,) 'S.$68)!!* C #! "!! 'S.$((.)* 8&< %% %%# #!!!! % 4! 'S.$.,()$ %" 'S.$..() 'S.$.,.)$!!!"!'S.$.60)*=$#!%'S.$.:)$ #'S.$-)!'S.$69)* # %2! %$ % %! # 'S.$.(6)*

78 Résultats 9&<! %%! &% T!! ' <)* & 4 " 80! 'S.$:.)*!!!!#T!! %'S.$...()*!!!% &%T!!'S.$.,)*!!! 'S.$...6)L?U "(.! &%T!!* T!!!"!! *6'(($(,/)!!0.'::$::/)'S.$...()*

79 Résultats \\<T! <T!!*!* T!! M = 'S06) 'S66) <'5) -;$(8'(8$8.) -9$;.'(:$,9) 5 5'3TI) -,T(- -8T(; 5 '/) -,'6($8,) -.'0:$-:) 5!'/) (8'00$6),.'66$6) 5 >%'/) (('(../).'&).$.('5) #'/),6'96$96) :',0$,6) 5? 5') (,'-&(6) (-$6';&(6).$...,'5) '5) (. - T - (:$:'9$;) (9':$() 5 _(. - T - '/) -6'6($-9) --'0:$6-).$.,'5)? (;,- 5 =# (. (, 5 %% ') =!% % '/) ($6'.$69),$('.$:,).$.(6'5) (,',8) 60';:).$.,'5)

80 :&= # Résultats < # '%%$ R $ $ %$ %$ % )$ %%'%)$!* \\ #* M 5!! = 'S69) 'S0-) 3% e : ( %, 9 5 >%,, 5 < =% : : 5 A&<<@5>1M<>> <<@5>1M<>>! #!* 5 # "! $ 0! "?U$ %$ &%T!! %*

81 Résultats \\ \\ I# I#!*!* # 1 # % 1 1 = = &5?U.$:,.$.-.$,;.$(&.$:.$.( &< :$-6.$(( & & &! &>%!.$-:.$.0.$,: -9$-&-9$:.$., &=!% 9$06.$8- & & & & (.$0,.$9- & & & % &T (-$-0.$..6 6.$(,,$:&[(...$..( & _(. - T - '/) (.$0-.$., -$0( ($80&9$,..$.(

82 5 55

83 Discussion '<)# * &>=>1?> >=>1?> <& > > > $ $.$8 0 (...',0)! 7#"'8:$8;)* % # C! 7"%%2" =5=* < 1$ f! f! $1g g*!" ($6(..*...%"" (./%* A&<?>>?>1>5 <?>>?>1>5!%#&"4 * %2 7$ # *<&",6$# '9.)*

84 Discussion! 4!!%2* >,..8$ >$ I,$,-T(...'0)$, ":0/#'6;/)#',6/)*! '69)$5'0.)$3%2 '-:)'9()* \\M = V4,..8'9( '9()* < A."( 5 >%% ("- 5A 5 >%% (", 5,",0 5 <[, %2

85 Discussion \\ \\ \\ \\M I#"%2$ I#"%2$ I#"%2$ I#"%2$ 4',..8$>$I) 4',..8$>$I) 4',..8$>$I) 4',..8$>$I)'9( '9( '9( '9()*?4')?4')?4')?4') (6 (6 (6 (6X,0,0,0,0,6,6,6,6X-; -; -; -; X [80 [80 [80 [80 (-( (,- -,-,0. (-68 I#!'/) I#!'/) I#!'/) I#!'/) 3*2 * * 5* 5*. :;. : - ((, (( : ; (( 8; 6 6 -( 0 0; (. \\M \\M \\M \\M '(;;8",..8> '(;;8",..8> '(;;8",..8> '(;;8",..8>XI) I) I) I)'9( '9( '9( '9()* A A A A 'T 'T 'T 'T (.. (.. (.. (...)...)...)...) (;;8 (;;8 (;;8 (;;8 (;;9 (;;9 (;;9 (;;9 (;;: (;;: (;;: (;;: (;;; (;;; (;;; (;;;,...,...,...,...,..(,..(,..(,..(,..,,..,,..,,..,,..-,..-,..-,..-,..0,..0,..0,..0,..6,..6,..6,..6,..8,..8,..8,..8 3*2 * 5* 5* * 99.$(-,:-.$0; 0;9.$:8 (,,.$,( 9..$(, 8..$(.,;..$ $;; (;0.$-- 60.$.; 0;.$.:,98.$ $;6 (68.$,9 6(.$.; 0:.$.: -,;.$68 09;.$:, (((.$(; 68.$(. 06.$.: -6,.$ $;( (6-.$,8 69.$(. 6;.$(. -;(.$ $:. ((:.$,.,6.$.0-9.$.8 -;,.$ $;6 (,:.$,( 6..$.9 6(.$.; -:-.$80 6:;.$;: (,-.$(: 00.$.: 6,.$.; -0:.$6: 698.$;8 (.:.$(: 00.$.: 80.$(( -8..$6; 686.$;- ((8.$(; 6,.$.: 09.$.: --;.$66 6,;.$:8 (,,.$,. 0:.$: (.0: (.0: (.0: (.0: ((9. ((9. ((9. ((9. (.:; (.:; (.:; (.:; (.,- (.,- (.,- (.,- ((0( ((0( ((0( ((0( (.80 (.80 (.80 (.80 ((9, ((9, ((9, ((9, ((:: ((:: ((:: ((:: ((,: ((,: ((,: ((,: ((6: ((6: ((6: ((6: (.:6 (.:6 (.:6 (.:6

86 Discussion $ 0, * #,, $! #!; * # H %# '6 )$ 1 '0) 5%# '()$ 5 < '()$3%2'.)* \\M 4 4 ',..:X,..;,..;)* %4 (6X,0,0,6X-; -; 0.X80 80 =# 6 ( (8,, 1# 0, - ; 5#h%# ( %#.. ( ( 1 - & ( 0 5< & & ( ( 3%2 & & &. 1 1 # #! (::9 U% $ * $!% % %%'9,$9-)* %# #" #"'90)*

87 Discussion # (- $ %!! <$A$ $@i (-6* &%%! "! %!* %% j!! %E %E!% '!!#%#! ) '9,)* "#"!C "* R!! %'90)'<M%)* *! %2 7(8,0';./)*< 4$#! " (./ 4 0. * " #$! %!$ "* A $! # '90)*

88 Discussion 1H& ' 1[.$.6) " " ==,$ # #! $ " * $ " % ' -?)!% '96)* %% L A '98)* = ';(/)';(/)'-8)* k#"!#$! %#!' # < )!'<$ $@$ i (-6) 4! 7 #!'0)*!"! % $ -7" # $ 2 #! $* 5# 5# 5 #" $ 5$! '!-./ )* %#

89 Discussion # ;.,- % * A!'%$$)$#!!! *>$# " %2* " # # * " # # ' 4 )$!!'! # 86)* > 7* A # $ # " #!!$!! # $ # 77*! $ " #! C (./ Q # # #$$-./ * >! #$ " * # H& 7* #"? " " '==)* % ==

90 Discussion ($,, D#$&"&! #" %!$!!$ & *! "!'99$9:$9;$:.)* H&$!&"&!?$" H& % ' -?)* % -? " %* -?' )!#':()* ##$! " #* >,...$! = M9'=!)# %2 $, $ >&! $ " " # %2 4!! '0)*!! 86 *! # 1 " <# * > I$! ##,-!6% $!! $ %2 $ %2$ %#$$#$ # 7

91 Discussion!! " #*! C " %* 3%2 3% 2 "? $ & *5 *% 8$$$$*! # % H&! %H&==* " 3% 2 ".$.:T(...,..8'0)* >!# % $! $!! & 3% 2 %2 (;;,$ " 3 $ #%$# ':9/)(;;8*>,..6$%$ $$* %$$!"':,$:-)* < 1$ $ - "%% 2,..:$ 1$ 4 "! (!87!,..9*

92 Discussion H& H& #* -." 0./ %* ==!" H&':0)* 5# 5# #$!&* $*!! %$ % % % * * % % 4" % * %!%$!! " #* =!$ %#$ % % %E* E$ &&%D#!#* C*>%$!&$ 74$7%2 $ %2 $ & # $%* "5# * $4(-/*

93 Discussion! $ # # '9;$:6)* #H&%#$" 7 " L # H& %2#$==':8)* 5%# %#? $ $ * %# "! '% ) %# "!* %!!! % $"!$ # " % %2 7!!L # #'80"(../)%#'(;"00/)':9$::)* "%*>#" % " '5<1) %* = % " '5<15) * = $%!* %# " #* H& "

94 Discussion ==* H&!C % &$ &!#$ *! "%#&* 5<17#" M!! $ # C 7 ':9$:;$;.)* " $ # 7 '$ )';()* 1 1 A "? $ $ W%$##!(::,* %#! *>" M3 #$ $! * <7%$ $ "!! %1*$! %* $ #5$j! 7#*<1$ M3 (;;( 5( 15$!!-.

95 Discussion...!%#*#" # 1$!%$$E #!%';,)*!* %# * %# # K ';-$;0)* 5 5 "?$$ &$ -9] *>"$!!! %#$%* l!# ' 3) ' )* % %! ' M)!* #! % $! &!*&!" %2 7 $ # %2 7 $ 7 %2 7 *!*

96 Discussion! '!$ $ %)$ *!C$ ^$ #!! %#* " *>$$!$';6)* &I< >5I<M5<5<5M>>>1>?>5 A< >>>5 %E "! $!!$!!* $ % " " #!!$! C '$) "#';8)* T " % #! ';9$;:)* = $"#! %* %2 $! #$ # " %$ " %#

97 Discussion * >!!! % ';;)* > %2 $#"#7'(..)* 4 " 8. $ $ $ $ # * >$ #%!!! " $ #!!'(.()* $ (: '(:/)! 4$ " % ; ';/)$ 9 '9/)"$6 '6$/)! $ 9 '9/) $ 8 '8/) $, ',/) M**3$ 0 '0/) %#$0 '0/), %% A%K%* & +> <&<?> <?> 4! #! * 4 " 6. "!! ##!!80 1A %'0.)*

98 Discussion! # 0;- 1A $ " 4 # -9/!(9/4"8.'8)*!$4 #!'0:)* 4 #!!* A&><>< 5 > > >!%2((";:/* % #!! $?U" (07#*<$%$8;/?U "(0" $ (0/ ',8$(.,$(.-)* $;9/!?U "(0$(0$0-/*! K #! " #'89$(.0)#!'6$8)*MAO*?U ((`-$?U! "!!!'0:) *

99 Discussion % #$ &## #*!#00"66/ '0:$(.6)* $ #&, E 0# %$!$ # * # # # "##"#'0:)* # $#!,0";:/'(.8$(.9$(.:)*< *9./!'(.;)*#%!%2:8/8.9:/4';8)* &C!!'8)* %#$ $ # Q!! *! %2 -, " :;/ L:9/MAO',8$0.)* # T!! $ #*>,,:-/'9,)*< * # -./ '(.;)$ # %290/%',8)*

100 Discussion! # # * $9-/#$8(/! %$ 09/!*!!*! # #!!* &5?>5>I <5< 5<!## L## 4# R!$ $ #! * < C$ C # 4$ # # # * = $ #!! $ ##* '8)$ 99 0;-',:/) (,'0/)! 4* " #$

101 Discussion W'89)! # %2,6 :.',:$9/)L $ ## "! ###! *MAO '0:)!! --/ #$ $ T 4 #!! # #!!* $ # --/!!!!'S.$69)* >& M55 > $!! %2 6 " -(/ % %* > # " ##" #'(.9)* C% 4$!! '89)*! $ #!!! "!! # #! '0.)*!$!!!,0 %!! "

102 Discussion '8)$C<'((.)$!! #! "!!*MAO'0:)$!! (6/ % "!!"% ##! * #!!#!# -8/!!! S.$0;* I&I>M> I>M>!# ##&'(.;)*>86";;/ *>%299/7MAO ',8$((()$:6/&(;;;'(.;)* $9;$,./!"*?&5?>5 <>5 %-"6(/* $!%$M AO ',8)$! " #$ # 7#" 96/ *! &!#

103 Discussion 6/ ',8$(.8)* % $ $ " # 7'0:)* $%2:':/)$ 0 '0/)! #$,! #$,',/)* # ##* 3&> 3> 3>>=>>>> %%% *!! C # 7 " * $ 5 %%! # " C "!!* %% #$ '((,)* ##%

104 Discussion (&I# &V V $"!$% $ % * *! V$ # #'((-$((0$((6)* &DV DV 7 " * > # &!!!!$ $ $ $! #$#'((6$((8)* &%# %# % # 7 * > $! *!&#* $"" "%#% %#$'((-$((9$((:)*

105 Discussion &#% " #V*>!!# $ $! %* >! % #* > $ # $%$$'((9$((;$(,.)*,&I% & %D! *$%D * C! K#'(,()* &%% %% %% C %% #! *>$$$ $%R!'C%!$ )*

106 Discussion &#$ &% *# AC, C %'(,,$(,-)* $ %2,6 ',6/)* %&#!;';/)$! 8':/)$!" %%0'0/)'(/) * &1<I>5<55@5>1+>5 1<I>5<55@5>1+>5 %#!C % * M AO '0:)$ % "(,.$ " 8. % # " 8.3 " C "!! # #! L! " #$ %!!* #,:.% # " ;.%'(.0)* < *'((.)$,./ % "!! ' # #! )$C#!!*

107 Discussion (( '((/) % $! %! "!!* &>>>5>\<1>5 >>>5>\<1>5 1=>1><>5 # # " 7*! # 7!$ ### * <&<= 1A<>! * > C % *C* (&%# %# $ # * $! &0&6-&0$! #! %$! K *! %#$##* %2$!,"6

108 Discussion $% C* >%&$ # #* C# %#%# C!! Q $!#"='-)*,& &<# $ # F %G* " % $ Q,.. T - '(,0)*!"#$! ##$"#% F 2G " #$ %##$#7 # ## 2! * =$ ((!$%!'-)* --/! $-;/! $,:/ (./ %%#*

109 Discussion &!_6T - %2*!6..T - " %* "(...T - %2 :9/ ;;/ (.. TY* %(..TY!'(,6)* # #! '%(...T - )" %* $ %"%!! &>#* &<%* &>!* " #! % " % C "! " '-)*!" 4 " #'89)*! # $! '(,8$(,9)$ '0:$ (,:)*

110 Discussion "(...T-#7'89)* $%6..(...T - %2;/$"(...T - %26;/%"(..TY!%2 8,/ $! % 9:/ *%"!* &A% %# $!"#'-)*?%?%! * #$ %C##C! C*%* > $!# %$ # %!* $#* %!'-)*!! %% % '89$ (.0) L % T! # "!! '0:)* %% C # % 1A $ # 7

111 Discussion %%%29,/!* =% + " %$!*< $.$(6".$06T'-)* A!$ # %%!'(,;)* %"-T" '8)* " #$ %%! "% #'(.0)! C M AO '0:)* %# %% %2 9-/ * &A A >, >?* %# $ $ J* #%#! 8. ;9/ # % (../

112 Discussion # $ $ 0. 8./! * %#%%#C #*?! % $! % (../ #* O$?96/!! " 6./! * 5 %2 7 9,$,/?6./7K#$ " #$ 8:/! "?'-)* $!"(;/ " * C # #* $! #9,/#"* # * =!$ $ % $#$#!* 1%$,0" 0:% * $ %#

113 Discussion '-)* $ % #! #,8$6/ *! #" * $ "! K %!*## 4!$C#% * C " & 1A #*! " $ # #! #j% #7! '9$ 0.)* %% 2$ $ 7%2* $!#-;/* >##$! $#5*!* 1*!!*

114 Discussion!%#!%#!%# $$ * %% =%# # $# * >$ # * C 7! # " #$! 7 %!!* $ $ * #" $ C *!! * >! 6. (../* 3$8-9.$!,:$8 :8$9/ 9. ;;$0/!* = $!(- 6; *!!!!! 9

115 Discussion ;9/ 9:;;/* #J'(-.)* = '= %) 1C#$ %# = %# * > $ %#$,0T,0 % '(-()* #%# * > $ % %# $!!$# #'?$)* # $ = 7$ $ C '<(85)'(-,)## *!,..0",..6' $A)$=$!= '*$5* $ 3* 2)!!9( $9.= ';:/)* >! %$ -9;( = L%0.$:/'(--)* $= *

116 Discussion -&=E =E # E -8% 0:% %#*!$! # % %# *5!$7= E* >!%$!! 0:% #$7* < $! #! # #* > $$?!C,0%# '8;)* A!$ 6- ;.! =$ 7 * #="'-7)* $ 6 '6/) E*

117 Discussion A&<>5>\<1>5A?+>5 1=>1><>5 (&3 ##!6./%!!!"#! * %! Q '_ 6/) #* 5$! % $%# * M AO$ %! 88/',8)*AO$%! -;/'(-0)* $%#*,&= % % %D &!,0%$7! $ #! '(-6)*! " %!!,0%$ # # #!*!! %C$

118 Discussion! (,",0% *! $ C! $ j C * $ #!$ ##!# # * $ " # '(-8)* $9." (../.$,"6T)! (../ '(-9)* #! % * ".$6 T %* = $ # " =!"!'-$(-:$(-;)* $#6* -&< & = = % V $ % $ " &8$ &C

119 Discussion " '(0.)* 5,0 " 0: % $!* & (;;:$? #!;,";0/'(0()* $ =%2;./! :,/* & f%$"(-6t"%v$ f! * % f f #f%"--to*! #" %$ "<3# "%!*<!#W$! %!$!!$ % & # '(0,)* 5 =&A$ # %"!"! '(0-)*

120 Discussion $ %$ %!!* &=< >>1<?>> > >>A<><5>51>?>5A< A< >>>5 $ 1 %! <%% <%% $ # # #* > $ # ##!=$ % " % 8./ '(.-$(00)* > $!= %$##!!'(06)* = 5=I'(;;8)'(08)$ = $ C # # # % #C* < $ "! = %2 # #! Q,"(( 355 '<)*

121 Discussion E $%#$!$%#*!! C # "'?Ub(,)* #')* 3$#9:/!='-()* # "!! &" =*!! & " = $ ",$9 # $!$ T#'(09)* %%4 < #$#!* > $!! #! 7 #* >!%$ '#$ %$ )$! ' )$ C E #!!$#$ " %% 4$ #! C ' $ $!)$!'%%$ )%#'R $%%)*

122 Discussion 1 4* > %%$ # C% # '1) # 4!" '()* %% % & %% 7 " # " * V$ 1 7#! 4D* %#$ 1 # %#* %C!#!! " * < #$1! '(0:)* $ 9: '9:/) 1 * 6. '6./)! " R $ % $ $%%$%%*! $ " %$ # Q *

123 Discussion # '1) # * $! # =$ 1 1 C"1*= $ 1! '()* $(('((/)1! $ * > %20'0/)-* M&<=5>> 3<?>3><=>+>>51>?>5 A< >>>5 %#!!*<!$"(9(... *!! (- ",9/ % ',0$,8)* <&<A3><=> <A3><=> (&<% <%# # < $ % $ " * <$ %

124 Discussion - % % #! " %E$##E',9)* % # 4$!' \\M)* \\M \\M > '(0: '(0:)* 5 A % <4 I A % % 1# =# =# 4 =% =#$ $ $! #%D * # 7% $ 7 (.(.. 1(.-. 1A'(0;)*

125 Discussion (;;85=I '(08)! &> $ # T! m55 -?* m5 # " '=5=) -?n!* m5 n? n 2* m51 -?* &>! -?!*!!!\\\*

126 Discussion \\\! '9( '9()* 5!X < = 5XI I (;;8 >#T!= -?=5= T! -?nm 5<!? 2 5* -?! -? X= =& A (;;9 <(8&8.<[8.n -? <[(8#'$$ 4$ )n -? %4[(8!n -? >& (;;9 (:&6. -?'5*$*) 6.n -?'5*$*$A?) n2'* A?) 4 %!n2'5%#$a?$5*) A% (;;; =%##2 <%#4(:&6. -? =$$%#! 2!!=5= -?n! #?2 5#? -?`!'=5=) A?n <%A%,..- -? n%274! n!`=5=

127 Discussion 5<,..0 5<,..0 '(6. '(6.) &5 -?n!* & -?* &?* &5?* &3%2 -?* &>%% -?* (9 %#&'5=I,..;) '5=I,..;) > % '[ 6. )$ % V *,# * " #* > " # %2 $ 7!"%- 7* >$"##!,..:'_(/)',$(6()*

128 Discussion \\ \\\ ( V ',9)* )* > 5# '?n) 5 # '?&) 5 'A?n) 53*2 'A?&) 5>*'A?&) 5- <# m -.. TOT7 M$ 0 $!%6.TO(%mm (..TOT7M$(,,.. TOT7 M$ 0 $!%6.TOT7(%mm 96TOT7M$(, <,.. TOT7 M$ 0 $ n? -"6TOT7M$(#7,.. TOT7 M$ 0 $!%6.TOT7(%mm 96TOT7M$(,,.. TOT7 M$ 0 $!%6.TOT7(%mm 96TOT7M$(, n -"6TOT7M$(#7? > 5! -.. TOT7 M$ 0 $!%6.TOT7(%mm n (..TOT7M$(, -"6TOT7M$(#7 5-? <!! mmm -.. TOT7 M$ 0 $!%6.TOT7(%mm n (..TOT7M$(, < n?,.. TOT7 M$ 0 $ -"6TOT7M$(#7 m7 %2 S(,$ S0* mmm 7 %! C K* mmm $! $ %%# '4T)*

129 Discussion $ -?;9$.,/$68/ $"!(;/$2-/$" (/$2"8/",/*;/* %%#!!# # # -?*! "# "$C$ %(6TO * > #$ -?*,& # $ '9($(6,) - 0"97#* - (."(07#* - 973%2* -,( 7 $ >%%* -&1% >!!$ 7 % # ' \\\)* # # C #

130 Discussion!'L!)$ % " # (07* #! ',9$(6-)* \\\ # #',9 ',9)* A$ 1 _.$(T 1 d.$(t 1 _.$(T 1 d.$(t 5 # 5 $,..TOT7M$0"8 $ -?$ (."(07mm ",..TOT7$"96TOT7 1 -?_.$6T M$0"8-.. TOT7',..TOT7 1_.$6T)M$( (."(07mm,(..TOT7'96TOT7 1_.$6T) < -? 0"97mmm $,..TOT7M$0"8 $96TOT7M$(, < " $-" 6 TOT7 (,(7 M-.97 < (0",(7 >%% $ ",,(7 7%2-3% 97 2 mm =E(. 7!!' 0: %) #"%- ' 1b.$6T7)' )L mmm=e07!!'0: %)' )*

131 Discussion > " #! #! 0:&9, % $ " # %$ E * # '$)* % -! " $!"'(.TO(,%%2$,. TO (,% %2 )!'(6 TO (% %8.TOT7)* 7 % # &" 0: % # &M ' $#)L &%%L & % - $! " 1!&"&!',9)* A& 3><=> % 7!! #* 5 &!#*

132 Discussion & % %2 # $ # 3% 2 # # 7!X!X#*! E %2 -.( # % '! X! X #)"!# ##": *%! %2 " # # # D* % %2 K #! '(.TO%2$.$(6TO%28% 07)',9$(60$(66)* 7%$! K" 7# - # %2 " # " #$ %2 " #"3%2* - # #

133 Discussion %2 - " (, * j ',9$:.)* $%"%K -(/* &<>5<>1>5 <>5<>1>5',9 ',9)!%# # * $ $ #$3 $! %#* %# "!$ 3 $ %& #$!%*!!!!!!7 #!* %4'3 ) 3 # # " #!!!* 4* #! &5!C",.X-.]* &5*

134 Discussion &M#* &#* & %&#$! %* &%!!# & * &!% 4! #! %%" "* &&($6T %#! %!* % # %% %$ $ % *! $" %%%*!%# % &V$ L & D V$ # L % C #!! 0: %

135 Discussion %* &> $ L &% %%! * 5 $! %$ 11* > %$!&#* %2 6$! 7* % %# %!! %*7# %! *!* M&>M >M <&1<> 1<> 5!=&A(;;:,..,$",(/*!! " # ' # ) # " #'-./!9/)'0)* $"0-/ # 9/* + # 6/$ #,/$ -/$"%#'(/) *

136 Discussion A& 1= <5>5>+>>5 (& # #!! % '((X(;/)$ # ',; X 0,/)!!! Q $!#!80/"96/* #$ R $%% 4'(68)* % =&A$! (0/$#'%$%$ 4)6./(6/',8)* $ %2(0/ $ # '%$ $ $!$ #$ )! %2,;/ $!!-8/* 4 " R $ %%$ $ %$% $ %! %2 6./ *,&5## # ##%2!! #$ #$ $ $ # " #,;9,/'(68)*

137 Discussion # # -./ %'-/)$ %'9/)$4',:/)* %! %2,,/!! '-(/)$',(/)$! '(9/)'-(/)*> * '!)!%2,9/ " #! 0/ " #'(69)* $ # $ #! j #! * &1<>5>5M>5=<>5<> >5M>5=<>5<> 5> 1>?>A< >>> '(69 '(69) <! * $! %#%- <%E > # # $! % *%!?5*?5 # (' )L,'! )L - '!!! )L 0' $!

138 Discussion! )L 6' )* =><& #$ 4 % #*<(67 * =%1%# %*>"1$%* >#* % # % * 5!! * %* 1! $! * 5!>>?* 5!* =%#%%% '! 4$)$$^ >!" >##* # % * 5 #$! # 7#" &$! "!*

139 Discussion >!! '% " 4)$$!$!* >!!# M ')L >% #! % ') T %2'#<%%)* 1!!==5'7 )$* &5+>> 5+>>> > M>>=>M>5> <>! * > "! '$ %#^)$#C%%#* < A5$ " # &* & " %% %#* %&C # ' % %4) &%%#%%%*

140 Discussion & '1 1 4 %)* >"#$! #<$A $ $% "$A5 #*!"# # " '4 [ 86 $ $ $ M3 $ % $ )$!#!#",-!*!! " # * >!%$"%K#! &# %2 % % #'(0:$(6:)* =$!7#!' 3 $ #$ # <$ $@ i(-6)$! '(6;$ (8.)* > $!!!!' )$ $ "! %!')'0)*

141 5

142 Conclusion " &*! %%#* # # % #C%* $! " " #! '(0:)* $"!=$:9$(,/L# #!!# 0-/* > #$ 9! -?U* - * - % - =!% - %_(...T-* - %[-% - "! T!!*

143 Conclusion = % & * &!* & 1! *

144 >51>5

145 Résumé >51> 1 # %#$ 7#"%" &* > 5*!$ *!!$(..! < 3 % $ k!,..:,..;*!"!!* >!$ %&,*(.. $ 8:% -, $! & ",$(,$ 4 -:$09 *?U" (($(8`-$.0*%(-0.$69`,...T - * %,$,. T$ 0,/! 5* ',,/)! # ';/)*0-/* >!$ K! -?U* - * - %

146 Résumé - =!% - %_(...T - * - %[-% - "!T!!* >!$! 7! %$$%_(...T - &% T!!*!$#!$C J " #$ " 7! $ $# %%# %#! * > $ % j %$# C %$ %!*

147 Summary %$ &# U % * % 5 * %UO$UO%*i!(..%>%! 3 % $ U k,..:,..;* %! U 2 U %!! % *!$%U2% %&,*(.. U$8:08UU%#,$(,$ %! U -:$09 * %?U U (($(8 `-$.0* %! U(-0.*69 `,... T-* %! U,$,. T$ U0,/U%5*',,/)U *';/)*%U-0/*!$U &<U?U* &%* &<!_(...T - *

148 Summary &%! T %! * &=%O* &%2=* &%[-%! $ % %O$ $_(...T - #% T!* I%UO%%%%$%!%7 %$% %* % %% & %!%* $%2 U%%! $U%%%%%%% %*

149 !"# $%&' ().(6#!, 3/ 1 8$(* +,-!,.+/%0 1, 2#"# 345%6#%,(7+" 8,(7+" 9* +#::-;%<.(6#% (<+!,DEE %C):%:10, 8%=>#?3&@+?03#>A$ + 0!,.+F$@G11H!F #I()J:K$(&K! >! 1H+ J(41 10C # +O# P&, 3& 8(,-%C(#", 9%DEE0V 8STUL4;R<03&+O#.1%:1J4!, 10C(6:J1,/8%0:XMZ[\(AY:(#+#J1,.V+,XLWM,(7+" #0 8 X,a@G% +/LEEE]DX[EZ`\%):(#%^:_Q/XZE[]DDZDWJ(41 %&2,e!,d[L$%,(7+"&Cc+8+ ab+lzle<!+y:(,/ 8d[X$(%Q_Q/8gdNf%<.(6#& gdllf% (<+.(6# l$ +O#13&&j$(%Q$k(&,36.+7h#3,(_&i# 8(6:O* FQ < m9m % m(% m <C(+(&2$0,-b1:?%V a%c0)'e% (b1: X 8,a%&4DEEE!m,3mKV%^:Y:(, C:_:!,+i/V% (5G#n+4o % (5G#3K0)KJpJ#C?

150 l$ +O#51,3&&j$(%Q$k(&,36.+7h#3,(_&i# 8(6:O* FQ % m(% m X 8,a%&4DEEE!m,3mKV%^:Y:(, 8<C(+(&2$0,-b1:?%V a%c0)'e% (b1: q(5g#+$(b1,?2>a%f+,3r$(%qv!3#>aj4!, +4o? q5h q>@ 0) Jp 3K +Q6 +# +O 2:( J#:,? 8n>4V.1,+4o $s+/%#av;/1knq(6, 3<:;&j$,+3&V1 2#$0)Jpb1tpeVbV1 2K($ 8 9* +,+,! V! q(5g#>4v.1,!!,!6#1k+q6?@("&;&)ee 8u +#J(45!,+i/-&C%ii%C$V-%C$

151 <>\>5

152 Annexes I< >5=5+>5>51>?>5A< >>>5 11<<>5 < 3A 3> <5<A< < 5!<$ 3% >>55>=<> >>55>=<> T^ ^^ <^^ ^^^^ 5^^ ^^^^^^^* <> >>5 5 I 5!M3 %! <^^^^^^^^^^^^^^^^^* I % 4 A % <^^^^^^^^^^^^^^^^^ =# 5#^^^^^^^^^^^^^^^^ <^^^^^^^^^^^^^^^^^^^

153 Annexes >>5 +>5! "#$%&$$ #'%&$((((( ") * (((((( +((((((((((((((((( $, $#&#$ -./ ) ) ) ((((((((((( * $ 0*1) *2 3 ((((!"#$%!! ' ( ' ( & ' ( ')* ( ><1< ><1< <!8% < 8% =! 1 7^^^^^^^^^^^^^^^^^^^^^**!! 7^^^^^^^^^**

154 Annexes A?><>>>>35=<5< A?><>>>>35=<5< ^^^^^^^^^ =% = <%! =^^^^^^^^ =>< 3>^^^^^^^**?@ < 3>'T)^^^^^^^** %T^^^^^^^^* >! < =5I?>1>>I> =>1 +> 5>= +>A 1>? +> 5<=3@ +> 3<>1=35 5>< 1@ A< >> <>^^^^^^^^^* < %? < I5$# < ^^^^^^^^^^^^^^^^ ^^^^^^^^^^^^^^^^ ^^^^^^^^^^^^^^^^**

155 Annexes =5>> 3<?>!# 7^^^^^^^ <%% 5 7^^^^^ <#^^^^^^^^^^* =!% %!%%^^^^^^^^^^^ 1!% 5 ^^^^^^^^^^^* <^^^^^^^^^^^^^^^* =!% <% => >5^^^^^^^ >=3<5=>5^^^^?@ =>=>5^^^^^* <15>5^^^^^^^* I5I1@ >^^^^^^ <^^^^^^^^^^ % %7^^^^^^ >M I<M<A> 5!^^^^^^^^^^^^^** ^^^^^^^^^^^^^^^^^** 7%^^^^^^^^^^^^^^^^^*

156 Annexes >153555>5=<> 3> 3> >5?>5> <5< '$4) '!$!) %! = 1 1 < 5 % >$

157 Annexes # >') > ') <! I#'=) I#'=) <! I#! = MAO,..0 ':;)'! 8;8 <? 5?A _(....$..6.$.( _.$..(.$..( #'?5S, 0) % % 3n =# % 3.$..-.$..; _.$..(.$.(.$.9 <[8.'.$.86) '.$..() # '?5S,0) W :9 '.$..(),..-'::) '!)?A '_.$..()? 5'_.$..() 3n'.$.(9) I&,..,';)! 8, <[6.'.$.0) '.$.()!'.$.()? 5_(.'.$.() 5<=< 3>'.$..8) # '?5S,-)" % <,.., ';.)!? 5'.$..6) %_(... '.$..,() 5?5'.$...8) =3! '.$...,) M# '.$..0) % _(... =3! M #.$..-,.$..,6.$..; <(;;:';;)!,8; '.$.-) '.$..() '.$.-)!'.$..() <5_;.3'.$.(6) =#'.$..6)! <5_;.3.$..8.$..6 _.$..( # ') (;;-',) '!),96 <[8.'_...() '_...()!'_...()

158 Annexes

159 !"#$% Annexes 55= >1>?>A< >>> $5 $!!$R $$## * 3= 3 <% nt&% <% nt&%! 5? = <% nt&% < % nt&%

160

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